CHD3 and ATPIF1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHD3	ATPIF1
Gene Name		chromodomain helicase DNA binding protein 3	ATPase inhibitory factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton	Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Cell Surface
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding	Enzyme Inhibitor Activity Calmodulin Binding ATPase Inhibitor Activity Protein Homodimerization Activity Angiostatin Binding ATPase Binding
	Biological Process	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Generation Of Precursor Metabolites And Energy Heme Biosynthetic Process Erythrocyte Differentiation Negative Regulation Of Nucleotide Metabolic Process Protein Homooligomerization Protein Homotetramerization Negative Regulation Of Hydrolase Activity Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions		90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1	4 interactors: CHD3 GSK3B PIK3CA UBQLN4
Entrez ID		1107	93974
HPRD ID		09071	16529
Ensembl ID		ENSG00000170004	ENSG00000130770
Uniprot IDs		B3KWV4 Q12873 Q2TAZ1	Q9UII2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process	Regulation Of DNA Methylation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Phosphatidylinositol-mediated Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Hypomethylation Of CpG Island Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Proteasomal Protein Catabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Hypermethylation Of CpG Island Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Fc Receptor Signaling Pathway Cellular Response To Interleukin-3 Regulation Of Developmental Growth Regulation Of Genetic Imprinting Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Negative Regulation Of NFAT Protein Import Into Nucleus Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Fibroblast Apoptotic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Regulation Of Cellular Protein Metabolic Process Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Export From Nucleus Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Anoikis Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Dendrite Development Regulation Of Protein Metabolic Process
Tagcloud ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	4alpha abcc3 accessible alu apoa4 apom canx elements employ femt1a genomics gstm4 hepatocyte hnf4alpha il32 ip6k2 junk microarrays nr2a1 originally pbms prlr prodh2 repeats sizeable socs2 superfamily tiggers ttr
Tagcloud (Difference) ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	4alpha abcc3 accessible alu apoa4 apom canx elements employ femt1a genomics gstm4 hepatocyte hnf4alpha il32 ip6k2 junk microarrays nr2a1 originally pbms prlr prodh2 repeats sizeable socs2 superfamily tiggers ttr
Tagcloud (Intersection) ?