CHD3 and ENTR1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHD3	ENTR1
Description		chromodomain helicase DNA binding protein 3	endosome associated trafficking regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytoskeleton NuRD Complex PML Body Centriolar Satellite	Cytoplasm Endosome Early Endosome Centrosome Cytoskeleton Midbody Retromer Complex Ciliary Basal Body Cell Projection Recycling Endosome
	Molecular Function	Nucleotide Binding Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding RNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding Metal Ion Binding ATP-dependent Chromatin Remodeler Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Spindle Organization Centrosome Cycle Regulation Of Cell Fate Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Stem Cell Differentiation	Protein Transport Cell Projection Organization Endocytic Recycling Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Cell Division Positive Regulation Of Protein Localization To Cilium
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression SUMOylation of chromatin organization proteins Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Drugs
Diseases
GWAS		Ischemic stroke ( 26089329) Macular thickness ( 30535121) Prostate cancer ( 29892016) Refractive error ( 32231278) Stroke ( 26089329)
Interacting Genes		101 interacting genes: ACTR1B ADH5 AIMP2 ATP5IF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CBX4 CPE CRCT1 CREB1 CREBBP CSTF2 CTBP1 CTTN ENTR1 ETV5 FABP4 FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MX1 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RETREG2 RGS2 RIF1 RNF10 RPL29 SAFB SAT1 SATB1 SERBP1 SERF2 SETX SGSM2 SIRT6 SKIL SLC27A6 SPOP SRRT STIP1 SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TRIM54 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBC UBE2I UROD VIM XRCC4 YAE1 ZHX1	12 interacting genes: AP1M1 APP AXIN1 CD99 CHD3 CSNK1E DDX6 GIT1 NOD2 SDCBP SMURF1 VIM
Entrez ID		1107	10807
HPRD ID		09071	15307
Ensembl ID		ENSG00000170004	ENSG00000165689
Uniprot IDs		A0A8V8TR54 B3KWV4 Q12873 Q2TAZ1	Q96C92
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Negative Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process SUMO Transferase Activity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process PML Body Protein Sumoylation Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Cytoplasm Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death RNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Gene Expression Ubiquitin Protein Ligase Binding Regulation Of Cell Development Presynaptic Cytosol Postsynaptic Cytosol Enzyme Binding Positive Regulation Of Metabolic Process Nucleic Acid Metabolic Process Nuclear Speck Regulation Of Neurogenesis Macromolecule Metabolic Process DNA Repair Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gliogenesis Protein-containing Complex Regulation Of Proteolysis Positive Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Stress Regulation Of Cell Differentiation Transcription Corepressor Activity Promoter-specific Chromatin Binding	Positive Regulation Of Catabolic Process Positive Regulation Of JNK Cascade Regulation Of JNK Cascade Positive Regulation Of Proteolysis Cellular Response To Muramyl Dipeptide Regulation Of Interleukin-1 Beta Production Positive Regulation Of Metabolic Process Regulation Of Interleukin-1 Production Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process I-SMAD Binding Regulation Of Primary Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Growth Cone Protein Serine/threonine Kinase Binding Positive Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Focal Adhesion Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Muramyl Dipeptide R-SMAD Binding Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Negative Regulation Of Signal Transduction Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Lipopolysaccharide Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Cellular Localization Frizzled Binding Negative Regulation Of Cell Communication Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Differentiation Cytosol Cellular Response To Molecule Of Bacterial Origin Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Catabolic Process Cytoplasm Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Protein Domain Specific Binding Amyloid-beta Complex Regulation Of Canonical Wnt Signaling Pathway Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Plasma Membrane Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding
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