WWP2 and USP7

  • Number of citations of the paper that reports this interaction (PMID 16713569)
  • 214

WWP2

USP7

Gene Name WW domain containing E3 ubiquitin protein ligase 2 ubiquitin specific peptidase 7 (herpes virus-associated)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 53 interactors: ANKRD44 ARRDC1 ATN1 CDC34 CLCN5 CPSF6 DAG1 DIDO1 EGR2 EWSR1 FAM189A2 FBXL18 HNRNPUL1 IL2RG IL6R LGALS9B NDFIP2 PAIP1 PDLIM7 POLR2A POU5F1 RASA1 RNF11 RUSC1 SCAMP3 SCN5A SCNN1A SCNN1B SCNN1G SF1 SFTPC SMAD3 SMAD7 SNRPC SPG20 TFAP2A TNK2 TP53BP2 TRAF4 UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 USP7 VASP VPS37C WBP1 WBP2 WIPF1 85 interactors: ACD ARNT2 ATXN1 BCOR BEND5 BMI1 CBX8 CHEK1 CLSPN CREB3L3 DAXX DNAJA3 DNMT1 DNMT3A EWSR1 EZH2 FAM175B FOXN2 HECW1 HERPUD1 HIST3H2BB HTRA2 KAT5 KLHL8 MAGEE1 MAL MARCH7 MCMBP MDM2 MDM4 MYD88 NECAB2 PCGF2 PEG3 PEPD PHLDB2 PICK1 PJA1 PLA2G2A PLEKHO1 PPARG PPL RADIL RARA RB1 RBCK1 RELA RFFL RING1 RNF2 RNF220 SMAD3 SUMO1 SUZ12 SYVN1 TANK TBCB TMPO TP53 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TRIM22 TRIM27 TRIM31 TRIM54 TRIM55 TRIM63 TRIM8 TRO UBC UBE2E1 UBE2S UHRF2 USP15 USP21 USP28 WWP2 XPC ZEB1 ZMYND8 ZNF423
Entrez ID 11060 7874
HPRD ID 03812 03950
Ensembl ID ENSG00000198373 ENSG00000187555
Uniprot IDs B4DHF6 O00308 B7Z815 Q6U8A4 Q93009
PDB IDs 1NB8 1NBF 1YY6 1YZE 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2KVR 2XXN 2YLM 3MQR 3MQS 4JJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accelerating  anticancer  biomarker  cascade  catalyzes  contributes  counterparts  deleted  dramatic  e3  encodes  final  homologue  ligase  ligases  malignancies  member  nedd4  neoplastic  oscc  osccs  pi3k  promotion  pten  ten  tensin  tumoral  ubiquitination 
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
Tagcloud (Difference) ?
accelerating  anticancer  biomarker  cascade  catalyzes  contributes  counterparts  deleted  dramatic  e3  encodes  final  homologue  ligase  ligases  malignancies  member  nedd4  neoplastic  oscc  osccs  pi3k  promotion  pten  ten  tensin  tumoral 
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  upregulation  usp7high  usp7low  vshrna 
Tagcloud (Intersection) ?
ubiquitination