USP7 and MDM4

  • Number of citations of the paper that reports this interaction (PMID 15916963)
  • 80
  • Data Source:
  • BioGRID (x-ray crystallography, unspecified method)
  • HPRD (in vitro)

USP7

MDM4

Gene Name ubiquitin specific peptidase 7 (herpes virus-associated) MDM4, p53 regulator
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 85 interactors: ACD ARNT2 ATXN1 BCOR BEND5 BMI1 CBX8 CHEK1 CLSPN CREB3L3 DAXX DNAJA3 DNMT1 DNMT3A EWSR1 EZH2 FAM175B FOXN2 HECW1 HERPUD1 HIST3H2BB HTRA2 KAT5 KLHL8 MAGEE1 MAL MARCH7 MCMBP MDM2 MDM4 MYD88 NECAB2 PCGF2 PEG3 PEPD PHLDB2 PICK1 PJA1 PLA2G2A PLEKHO1 PPARG PPL RADIL RARA RB1 RBCK1 RELA RFFL RING1 RNF2 RNF220 SMAD3 SUMO1 SUZ12 SYVN1 TANK TBCB TMPO TP53 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TRIM22 TRIM27 TRIM31 TRIM54 TRIM55 TRIM63 TRIM8 TRO UBC UBE2E1 UBE2S UHRF2 USP15 USP21 USP28 WWP2 XPC ZEB1 ZMYND8 ZNF423 42 interactors: AKT1 APP ARF1 ATM CAPN7 CASP3 CD160 CDK1 CHEK1 CHEK2 CSNK1A1 E2F1 EP300 LRSAM1 MDM2 MKRN3 MNAT1 PRKAA1 RAD54B RB1 RN5S1@ RNF115 SFN SMAD3 SMAD4 SMARCA2 TP53 TP63 TP73 TRIM46 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 USP7 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 7874 4194
HPRD ID 03950 04082
Ensembl ID ENSG00000187555 ENSG00000198625
Uniprot IDs B7Z815 Q6U8A4 Q93009 O15151 Q59FS6 Q68DC0
PDB IDs 1NB8 1NBF 1YY6 1YZE 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2KVR 2XXN 2YLM 3MQR 3MQS 4JJQ 2CR8 2VJE 2VJF 2VYR 3DAB 3EQY 3FDO 3FE7 3FEA 3JZO 3JZP 3JZQ 3LBJ 3U15
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
aberrations  abstract  along  attractive  cdk  cdk4  checkpoint  correlate  cyclind  developments  entered  highlights  kinases  logical  make  maximizing  mdm2  melanoma  melanomagenesis  p16  preliminary  rb  rb1  reactivating  reactivation  reporting  summary  targeting  video 
Tagcloud (Difference) ?
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mesenchymal  metastasis  nsclc  overexpression  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
aberrations  abstract  along  attractive  cdk  cdk4  checkpoint  correlate  cyclind  developments  entered  highlights  kinases  logical  make  maximizing  melanoma  melanomagenesis  p16  rb  rb1  reactivating  reactivation  reporting  summary  targeting  video 
Tagcloud (Intersection) ?
mdm2  preliminary