USP7 and RELA

  • Number of citations of the paper that reports this interaction (PMID 23267096)
  • 9
  • Data Source:
  • BioGRID (enzymatic study)

USP7

RELA

Gene Name ubiquitin specific peptidase 7 (herpes virus-associated) v-rel avian reticuloendotheliosis viral oncogene homolog A
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 85 interactors: ACD ARNT2 ATXN1 BCOR BEND5 BMI1 CBX8 CHEK1 CLSPN CREB3L3 DAXX DNAJA3 DNMT1 DNMT3A EWSR1 EZH2 FAM175B FOXN2 HECW1 HERPUD1 HIST3H2BB HTRA2 KAT5 KLHL8 MAGEE1 MAL MARCH7 MCMBP MDM2 MDM4 MYD88 NECAB2 PCGF2 PEG3 PEPD PHLDB2 PICK1 PJA1 PLA2G2A PLEKHO1 PPARG PPL RADIL RARA RB1 RBCK1 RELA RFFL RING1 RNF2 RNF220 SMAD3 SUMO1 SUZ12 SYVN1 TANK TBCB TMPO TP53 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TRIM22 TRIM27 TRIM31 TRIM54 TRIM55 TRIM63 TRIM8 TRO UBC UBE2E1 UBE2S UHRF2 USP15 USP21 USP28 WWP2 XPC ZEB1 ZMYND8 ZNF423 185 interactors: AATF ACTL6A AES AGO1 AHR AKAP8 APBA2 AR ASCC1 ASCC2 ASCC3 BATF2 BRCA1 BRMS1 BTK BTRC C1QB CALM1 CAMK4 CARM1 CCL5 CDC34 CDK9 CEBPB CEBPD CENPJ CHEK1 CHUK CNNM3 COL2A1 COMMD1 CREBBP CSNK1G1 CSNK2A1 CSNK2A2 DDC DDX1 DHX9 DNAJA3 ECSIT EEF1D EGR1 EP300 ESR1 ETHE1 EZH2 FAF1 FKBP11 FOS FUS GOPC GTF2B HDAC1 HDAC2 HDAC3 HEXIM1 HMGA2 HMGB1 HSPA4 IKBKB IKBKE IKBKG ING4 IRAK1BP1 IRF1 IRF2 IRF3 IRF8 IRF9 ISL1 JUN KAT2A KAT2B KAT5 KDM2A KEAP1 KPNA2 LMO2 MAP2K6 MAP3K7 MAP3K8 MAPK10 MAPK14 MED15 MED23 MED7 MEN1 MST1R MTPN MYC NCOA3 NCOA6 NCOR2 NFKB1 NFKB2 NFKBIA NFKBIB NFKBIE NKRF NKX2-1 NOTCH1 NPM1 NR3C1 PARP1 PDCD11 PGR PIAS1 PIAS3 PIN1 PKM PLA2G4A PLK1 PML POU2F1 PPARA PPARG PPP1R13L PPP2CA PPP2CB PPP2R1B PPP4C PRKACA PRKCZ PRMT1 PRTN3 PSMD10 REL RELB REPS2 RFC1 RIOK2 RNASE1 RNF25 RPL13 RPL23 RPS3 RPS6KA5 RXRA SAT1 SETD7 SIN3A SIRT1 SIRT6 SMAD3 SMAD4 SNIP1 SNRNP70 SOCS1 SOCS6 SORD SP1 SRF STAT1 STAT3 STAT6 TAF1 TAF11 TAF4B TAF6 TAF9 TBK1 TBP TCAP TCF4 TERT TGM2 TNIP2 TP53BP1 TP53BP2 TRIB3 TRIP4 TSC22D3 TWIST1 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBE2L3 UNC5CL USF2 USP7 ZBTB7A
Entrez ID 7874 5970
HPRD ID 03950 01241
Ensembl ID ENSG00000187555 ENSG00000173039
Uniprot IDs B7Z815 Q6U8A4 Q93009 Q04206
PDB IDs 1NB8 1NBF 1YY6 1YZE 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2KVR 2XXN 2YLM 3MQR 3MQS 4JJQ 1NFI 2LSP 2O61 3GUT 3QXY 3RC0 4KV1 4KV4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
balpha  bbeta  bepsilon  biochemically  casein  ck  complexed  conjugation  correspond  crel  ikappa  ikappab  ikk1  ikks  indirectly  initiates  locate  nonstimulated  okadaic  p100  p105  p90rsk1  pest  phosphorylating  purify  relb  s32  s36  serines 
Tagcloud (Difference) ?
accordingly  adenocarcinoma  bad  carcinoma  clarified  de  downregulation  excluding  h460  hbe  indicator  invasion  invasive  mdm2  mesenchymal  metastasis  nsclc  overexpression  preliminary  regulate  serve  squamous  stabilization  tumorous  ubiquitination  upregulation  usp7high  usp7low  vshrna 
balpha  bbeta  bepsilon  biochemically  casein  ck  complexed  conjugation  correspond  crel  ikappa  ikappab  ikk1  ikks  indirectly  initiates  locate  nonstimulated  okadaic  p100  p105  p90rsk1  pest  phosphorylating  purify  relb  s32  s36  serines 
Tagcloud (Intersection) ?