USP19 and RNF2

Number of citations of the paper that reports this interaction (PMID 23500468)
0

Data Source:
BioGRID (two hybrid)

		USP19	RNF2
Gene Name		ubiquitin specific peptidase 19	ring finger protein 2
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Ubiquitin Ligase Complex Euchromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex MLL1 Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Metal Ion Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity RING-like Zinc Finger Domain Binding
	Biological Process	Protein Deubiquitination ER-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Gastrulation With Mouth Forming Second Transcription, DNA-templated Anterior/posterior Axis Specification Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC	54 interactors: ABCB1 AMBRA1 BMI1 CASP3 CASP9 CBX4 CBX6 CBX7 CBX8 HIST1H2AB HIST2H2AA3 HIST2H2AC HIST3H3 KAT8 KMT2A L3MBTL2 MBD1 OTUD6A PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PGP PHB2 PHC1 PSMC4 RING1 RRM1 RYBP SMURF2 SSX2 TARDBP TFCP2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2J1 UBE2K UBE2L3 UBE2U UBE2V1 UBE2V2 UBE2W UBE3A USP11 USP19 USP7 WASH1
Entrez ID		10869	6045
HPRD ID		18278	07028
Ensembl ID		ENSG00000172046	ENSG00000121481
Uniprot IDs		O94966	B3KRH1 Q99496
PDB IDs		1WH0	2H0D 3GS2 3H8H 3IXS 3RPG
Enriched GO Terms of Interacting Partners?		Cell Morphogenesis Involved In Differentiation Cell Cycle Epithelial To Mesenchymal Transition Protein Ubiquitination Cell Morphogenesis Protein Modification By Small Protein Conjugation MRNA Transcription From RNA Polymerase II Promoter MRNA Transcription Positive Regulation Of Signal Transduction Mesenchymal Cell Development Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Intracellular Signal Transduction Mesenchymal Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Anatomical Structure Morphogenesis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein Ubiquitination Mesenchyme Development Regulation Of Intracellular Signal Transduction Regulation Of Nitric-oxide Synthase Activity Cell Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signal Transduction Stem Cell Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Mitotic Cell Cycle Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of TOR Signaling Regulation Of Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Stem Cell Differentiation Neural Fold Elevation Formation MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Apoptotic Process Regulation Of Oxidoreductase Activity Cell Projection Morphogenesis Toll-like Receptor 4 Signaling Pathway Regulation Of Catalytic Activity Cell Differentiation Regulation Of Cell Death Cell Part Morphogenesis Regulation Of Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Metabolic Process Positive Regulation Of Immune System Process	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Protein K48-linked Ubiquitination Cellular Protein Modification Process Histone Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Protein Catabolic Process Chromatin Modification Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Metabolic Process Chromatin Organization Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Transcription, DNA-templated Chromosome Organization Histone Modification RNA Biosynthetic Process Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Proteolysis Protein Monoubiquitination Negative Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Catabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Protein K63-linked Ubiquitination Macromolecule Biosynthetic Process Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression
Tagcloud ?		adenoviral catalytic chop collectively concomitant creating defect deubiquitinating display enhancement exerts fusion implicate isoform isoforms l6 localized modulated modulates muscle myoblast myofibrillar myogenin possibility raised regeneration thapsigargin unfolded upr	aldrich ambra1 arp2 associates autophagy becn1 cul4a ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott
Tagcloud (Difference) ?		adenoviral catalytic chop collectively concomitant creating defect deubiquitinating display enhancement exerts fusion implicate isoform isoforms l6 localized modulated modulates muscle myoblast myofibrillar myogenin possibility raised regeneration thapsigargin unfolded upr	aldrich ambra1 arp2 associates autophagy becn1 cul4a ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott
Tagcloud (Intersection) ?