USP19 and LAMTOR4

Number of citations of the paper that reports this interaction (PMID 23500468)
0

Data Source:
BioGRID (two hybrid)

		USP19	LAMTOR4
Gene Name		ubiquitin specific peptidase 19	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Lysosome Intracellular Membrane-bounded Organelle Ragulator Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Complex Scaffold
	Biological Process	Protein Deubiquitination ER-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia	Regulation Of Cell Size Positive Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC	2 interactors: LAMTOR5 USP19
Entrez ID		10869	389541
HPRD ID		18278	17380
Ensembl ID		ENSG00000172046	ENSG00000188186
Uniprot IDs		O94966	Q0VGL1
PDB IDs		1WH0
Enriched GO Terms of Interacting Partners?		Cell Morphogenesis Involved In Differentiation Cell Cycle Epithelial To Mesenchymal Transition Protein Ubiquitination Cell Morphogenesis Protein Modification By Small Protein Conjugation MRNA Transcription From RNA Polymerase II Promoter MRNA Transcription Positive Regulation Of Signal Transduction Mesenchymal Cell Development Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Intracellular Signal Transduction Mesenchymal Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Anatomical Structure Morphogenesis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein Ubiquitination Mesenchyme Development Regulation Of Intracellular Signal Transduction Regulation Of Nitric-oxide Synthase Activity Cell Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signal Transduction Stem Cell Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Mitotic Cell Cycle Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of TOR Signaling Regulation Of Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Stem Cell Differentiation Neural Fold Elevation Formation MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Apoptotic Process Regulation Of Oxidoreductase Activity Cell Projection Morphogenesis Toll-like Receptor 4 Signaling Pathway Regulation Of Catalytic Activity Cell Differentiation Regulation Of Cell Death Cell Part Morphogenesis Regulation Of Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Metabolic Process Positive Regulation Of Immune System Process	Regulation Of Cellular Response To Hypoxia Regulation Of Proteolysis Protein Localization To Lysosome Negative Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of TOR Signaling Viral Genome Replication
Tagcloud ?		adenoviral catalytic chop collectively concomitant creating defect deubiquitinating display enhancement exerts fusion implicate isoform isoforms l6 localized modulated modulates muscle myoblast myofibrillar myogenin possibility raised regeneration thapsigargin unfolded upr
Tagcloud (Difference) ?		adenoviral catalytic chop collectively concomitant creating defect deubiquitinating display enhancement exerts fusion implicate isoform isoforms l6 localized modulated modulates muscle myoblast myofibrillar myogenin possibility raised regeneration thapsigargin unfolded upr
Tagcloud (Intersection) ?