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DRAP1 and TK1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DRAP1
TK1
Gene Name
DR1-associated protein 1 (negative cofactor 2 alpha)
thymidine kinase 1, soluble
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Thymidine Kinase Activity
ATP Binding
Zinc Ion Binding
Nucleoside Kinase Activity
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Liver Development
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Nucleotide Biosynthetic Process
Response To Toxic Substance
Skeletal Muscle Cell Proliferation
Phosphorylation
Response To Nutrient Levels
Pyrimidine Nucleoside Salvage
Small Molecule Metabolic Process
Thymidine Metabolic Process
Response To Copper Ion
Digestive Tract Development
Protein Homotetramerization
Response To Cortisol
Nucleobase-containing Small Molecule Metabolic Process
Fetal Process Involved In Parturition
DNA Biosynthetic Process
Pathways
Signaling by Activin
Signaling by NODAL
Pyrimidine salvage reactions
Pyrimidine metabolism
Metabolism of nucleotides
Drugs
Dithioerythritol
Thymidine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions
22 interactors:
APP
ARHGEF10L
CDKN2C
DNAJB11
DR1
FEZ1
FEZ2
FOXH1
GTF2B
LMO2
NCK2
NFYB
PIK3R3
POLE3
SRPK2
TAF9
TAF9B
TBP
TK1
TNFRSF14
TTF2
ZEB1
159 interactors:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ASNA1
ATG16L2
ATP5B
ATP6V1A
ATXN3
BAG6
C14orf1
C19orf60
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CPSF3L
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
EEF1A1
EIF3G
EIF4A2
EIF6
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
FZR1
GAPDH
GDF9
GDI1
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LOC148413
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS
RBBP4
RBM48
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPT6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO3
TAF1C
TCTEX1D2
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR60
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
Entrez ID
10589
7083
HPRD ID
03796
01771
Ensembl ID
ENSG00000175550
ENSG00000167900
Uniprot IDs
Q14919
P04183
PDB IDs
1JFI
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
?
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription Elongation From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Elongation
Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Transcription, DNA-templated
Gene Expression
Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Histone H3 Acetylation
Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Cellular Process
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Viral Process
Histone Acetylation
Regulation Of Receptor Activity
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Internal Protein Amino Acid Acetylation
Response To Organic Substance
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Protein Acetylation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Protein Metabolic Process
Developmental Process
Anatomical Structure Development
System Development
Regulation Of Cellular Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Cellular Localization
Metabolic Process
Regulation Of Metabolic Process
Organelle Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Protein Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Catabolic Process
RNA Metabolic Process
Negative Regulation Of Cell Cycle
Posttranscriptional Regulation Of Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Protein Catabolic Process
Negative Regulation Of Cellular Metabolic Process
Cell Differentiation
Platelet Degranulation
Gene Expression
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Negative Regulation Of Mitotic Cell Cycle
Cellular Process
Biosynthetic Process
Regulation Of Cell Cycle
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cycle Process
Mitotic Cell Cycle Process
Axon Guidance
Chromatin Organization
Viral Process
Programmed Cell Death
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Chromosome Organization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Cellular Response To Organic Substance
Mitotic Cell Cycle
Cellular Response To Growth Factor Stimulus
Tagcloud
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Difference)
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Intersection)
?