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DRAP1 and TTF2
Number of citations of the paper that reports this interaction (PMID
12927788
)
7
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DRAP1
TTF2
Gene Name
DR1-associated protein 1 (negative cofactor 2 alpha)
transcription termination factor, RNA polymerase II
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Spliceosomal Complex
Cytoplasm
Transcription Elongation Factor Complex
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
DNA Binding
Protein Binding
ATP Binding
ATP-dependent Helicase Activity
DNA-dependent ATPase Activity
Zinc Ion Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
DNA-templated Transcription, Termination
Regulation Of Transcription, DNA-templated
Termination Of RNA Polymerase II Transcription
MRNA Processing
RNA Splicing
Pathways
Signaling by Activin
Signaling by NODAL
Drugs
Diseases
GWAS
Protein-Protein Interactions
22 interactors:
APP
ARHGEF10L
CDKN2C
DNAJB11
DR1
FEZ1
FEZ2
FOXH1
GTF2B
LMO2
NCK2
NFYB
PIK3R3
POLE3
SRPK2
TAF9
TAF9B
TBP
TK1
TNFRSF14
TTF2
ZEB1
22 interactors:
CDC5L
CDKL3
CLPB
DCP1A
DR1
DRAP1
HINFP
HNRNPA1
HNRNPA2B1
KIF4A
MATR3
MYB
MYBL2
NVL
PDCD6IP
PRDX4
SKIL
SMAD1
SMAD7
TACC3
TNIP1
ZSCAN1
Entrez ID
10589
8458
HPRD ID
03796
05280
Ensembl ID
ENSG00000175550
Uniprot IDs
Q14919
Q9UNY4
PDB IDs
1JFI
Enriched GO Terms of Interacting Partners
?
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription Elongation From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Elongation
Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Transcription, DNA-templated
Gene Expression
Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Histone H3 Acetylation
Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Cellular Process
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Viral Process
Histone Acetylation
Regulation Of Receptor Activity
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Internal Protein Amino Acid Acetylation
Response To Organic Substance
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Protein Acetylation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Heterocycle Metabolic Process
Transcription, DNA-templated
Negative Regulation Of Gene Expression
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cell Cycle Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Cell Cycle
Regulation Of Cell Cycle
Regulation Of Gene Expression
Cellular Metabolic Process
Mitotic Spindle Assembly
Regulation Of Nitrogen Compound Metabolic Process
Spindle Organization
Negative Regulation Of Cellular Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Dendrite Morphogenesis
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Transcription, DNA-templated
Regulation Of Cell Morphogenesis
Biosynthetic Process
Mitotic Spindle Organization
Positive Regulation Of Neuron Projection Development
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
Negative Regulation Of Male Germ Cell Proliferation
Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Response To Stress
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Dendrite Development
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud
?
away
bidirectional
coimmunoprecipitate
cotranscriptional
dcp1a
dcp2
decapping
edc3
elongation
ends
exonuclease
facilitates
localize
nascent
pause
paused
peaks
pol
premature
productive
redistribution
seq
shifted
spt5
termination
torpedo
tss
tsss
xrn2
Tagcloud (Difference)
?
away
bidirectional
coimmunoprecipitate
cotranscriptional
dcp1a
dcp2
decapping
edc3
elongation
ends
exonuclease
facilitates
localize
nascent
pause
paused
peaks
pol
premature
productive
redistribution
seq
shifted
spt5
termination
torpedo
tss
tsss
xrn2
Tagcloud (Intersection)
?