DRAP1 and FEZ2

Number of citations of the paper that reports this interaction (PubMedID 16484223)
0

Data Source:
BioGRID (two hybrid)

		DRAP1	FEZ2
Description		DR1 associated protein 1	fasciculation and elongation protein zeta 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex	Cytoplasm Axon
	Molecular Function	Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly
Pathways		Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)	Apolipoprotein A1 levels ( 32203549) Haemorrhoidal disease ( 33888516) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		31 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX1 LNX2 MCRS1 MORF4L1 NCK2 NFYB PICK1 PIK3R3 PLEKHF2 POLE3 RPL9 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1	18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SMC3 STIP1 TBC1D25 TEDC2 TLK2 WWC1 ZNF251
Entrez ID		10589	9637
HPRD ID		03796	09213
Ensembl ID		ENSG00000175550	ENSG00000171055
Uniprot IDs		Q14919	Q9UHY8
PDB IDs		1JFI
Enriched GO Terms of Interacting Partners?		RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity Transcription Factor TFIID Complex DNA-binding Transcription Factor Binding RNA Polymerase II Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly DNA-templated Transcription Initiation Regulation Of Intrinsic Apoptotic Signaling Pathway Protein-DNA Complex Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Protein-containing Complex Assembly Regulation Of Cellular Response To Stress Regulation Of Receptor Internalization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II ATAC Complex Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Autophagosome Assembly Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Nucleic Acid Metabolic Process Transcription Factor TFTC Complex Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein-containing Complex Organization Chromatin Organization Regulation Of Apoptotic Signaling Pathway RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Metabolic Process Cytoskeletal Anchor Activity Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Chromatin Remodeling TBP-class Protein Binding Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Receptor Internalization BHLH Transcription Factor Binding Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription Cis-regulatory Region Binding Positive Regulation Of Macromolecule Metabolic Process	Establishment Or Maintenance Of Cell Polarity Establishment Of Cell Polarity
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