HUWE1 and PIAS2

  • Number of citations of the paper that reports this interaction (PMID 20624960)
  • 10
  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology)

HUWE1

PIAS2

Gene Name HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase protein inhibitor of activated STAT, 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: ABL1 CALM1 CCL1 CDKN2A HDAC2 LAPTM5 MCL1 MYC PIAS2 POLB RNF11 SMAD2 SMAD9 TP53 UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 68 interactors: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CHMP4B CLDN2 CTBP1 DDX39B ELK1 ESR1 ESR2 FLI1 GFAP GFI1 GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 ITGB5 JUN MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 MYCN NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I ZBED1 ZBTB8A ZNF451
Entrez ID 10075 9063
HPRD ID 06608 06944
Ensembl ID ENSG00000086758 ENSG00000078043
Uniprot IDs Q7Z6Z7 O75928
PDB IDs 2EKK 3G1N 3H1D 2ASQ 4FO9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
293t  acts  alphaclass  androgen  ar  chaperone  clone27  coimmunoprecipitation  colocalization  coregulator  cytoplasm  e3  factorkappab  hek  hela  libraries  ligase  modulates  prefoldintype  sumoylation  termed  transcript  transducer  trapped  twohybrid  ubiquitously  uxt  yeast 
Tagcloud (Difference) ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  freund  heclin  hect  heinis  hek293  huge  kills  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
293t  acts  alphaclass  androgen  ar  chaperone  clone27  coimmunoprecipitation  colocalization  coregulator  cytoplasm  factorkappab  hek  hela  libraries  modulates  prefoldintype  sumoylation  termed  transcript  transducer  trapped  twohybrid  ubiquitously  uxt  yeast 
Tagcloud (Intersection) ?
e3  ligase