PIAS2 and GTF2IRD1

Number of citations of the paper that reports this interaction (PMID 12193603)
7

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PIAS2	GTF2IRD1
Gene Name		protein inhibitor of activated STAT, 2	GTF2I repeat domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus PML Body Nuclear Speck	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Androgen Receptor Binding SUMO Ligase Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Transcription, DNA-templated Protein Sumoylation Androgen Receptor Signaling Pathway Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Androgen Receptor Signaling Pathway	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Transition Between Slow And Fast Fiber
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		68 interactors: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CHMP4B CLDN2 CTBP1 DDX39B ELK1 ESR1 ESR2 FLI1 GFAP GFI1 GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 ITGB5 JUN MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 MYCN NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I ZBED1 ZBTB8A ZNF451	6 interactors: CDK20 EXOSC4 HDAC3 PIAS2 SMAD3 UBC
Entrez ID		9063	9569
HPRD ID		06944	08379
Ensembl ID		ENSG00000078043	ENSG00000006704
Uniprot IDs		O75928	E9PFE2 Q9UHL9
PDB IDs		2ASQ 4FO9	2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Transcription, DNA-templated Response To Organic Substance RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated RNA Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Protein Sumoylation Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cell Death Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Gland Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Protein Modification By Small Protein Conjugation Cellular Response To Lipid Macromolecule Biosynthetic Process Cellular Response To Stimulus Regulation Of Cellular Process Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Cellular Metabolic Process Cellular Response To Organic Cyclic Compound Regulation Of Cell Proliferation Regulation Of Signaling Signaling	Regulation Of Cell Cycle Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Protein Import Into Nucleus RNA Metabolic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Biosynthetic Process Response To Growth Factor Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Growth Gene Expression Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Osteoblast Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Stability Notch Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Protein Transport Evasion Or Tolerance Of Host Defenses By Virus Transcription Initiation From RNA Polymerase II Promoter Regulation Of Protein Import Into Nucleus Circadian Rhythm Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Ossification Regulation Of Protein Localization To Nucleus Negative Regulation Of Apoptotic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Programmed Cell Death
Tagcloud ?		293t acts alphaclass androgen ar chaperone clone27 coimmunoprecipitation colocalization coregulator cytoplasm e3 factorkappab hek hela libraries ligase modulates prefoldintype sumoylation termed transcript transducer trapped twohybrid ubiquitously uxt yeast
Tagcloud (Difference) ?		293t acts alphaclass androgen ar chaperone clone27 coimmunoprecipitation colocalization coregulator cytoplasm e3 factorkappab hek hela libraries ligase modulates prefoldintype sumoylation termed transcript transducer trapped twohybrid ubiquitously uxt yeast
Tagcloud (Intersection) ?