HUWE1 and UBE2D1

  • Number of citations of the paper that reports this interaction (PMID 15989956)
  • 126

HUWE1

UBE2D1

Gene Name HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase ubiquitin-conjugating enzyme E2D 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: ABL1 CALM1 CCL1 CDKN2A HDAC2 LAPTM5 MCL1 MYC PIAS2 POLB RNF11 SMAD2 SMAD9 TP53 UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 193 interactors: AMFR ANAPC11 ANXA1 ANXA7 AREL1 ARIH1 ARIH2 ASB2 ASB4 ASB9 BARD1 BFAR BIRC2 BIRC3 BIRC6 BIRC7 BIRC8 BRCA1 BRCC3 BRE BRMS1 C7orf25 CADPS2 CBL CBLC CDK7 CDKN1A CHFR CNOT4 CREBBP CRYAB CTNNB1 CUL2 CUL3 DDX58 DTL DTX1 DTX2 DTX3 DTX3L DZIP3 EP300 EPS15 F12 FAF2 FBXO2 FBXW7 FOS FZR1 GADD45A GSK3B HDAC6 HERC3 HERC5 HIF1A HSD17B10 HUWE1 KAT2B KDM2B KLHL13 KLHL2 KLHL9 LRSAM1 MAP3K1 MARCH1 MARCH2 MARCH4 MARCH5 MARCH7 MARCH8 MDM2 MDM4 MGRN1 MIB1 MID1 MID2 MKNK1 MKRN2 MKRN3 MUL1 MYLIP NBN NEDD4 NEDD4L NEURL1 NFKBIA NHLRC1 NR1H2 OTUB1 PELI1 PJA2 POLL POLM RABGEF1 RAD23A RBX1 RELA RFFL RFWD2 RFWD3 RING1 RLIM RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF122 RNF125 RNF126 RNF128 RNF13 RNF130 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF182 RNF185 RNF2 RNF25 RNF26 RNF31 RNF38 RNF4 RNF43 RNF5 RNF6 RNF7 RNF8 SH3RF1 SIAH1 SIAH2 SIRT6 SIVA1 SKP1 SMURF2 STAM2 STUB1 TAF1D TBL1X TNFAIP3 TNNT1 TOM1 TOPORS TP53 TRAF2 TRAF6 TRAF7 TRAIP TRIM10 TRIM17 TRIM2 TRIM21 TRIM23 TRIM25 TRIM26 TRIM27 TRIM28 TRIM31 TRIM32 TRIM35 TRIM37 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM55 TRIM63 TRIM7 TRIM8 TRIP12 TSC22D1 UBA1 UBA6 UBASH3B UBC UBE3A UBE3C UBE4A UBOX5 UFM1 UHRF2 VHL XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID 10075 7321
HPRD ID 06608 04267
Ensembl ID ENSG00000086758 ENSG00000072401
Uniprot IDs Q7Z6Z7 P51668
PDB IDs 2EKK 3G1N 3H1D 2C4P 2YHO 3OJ4 3PTF 4AP4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
accumulation  apoptosis  apoptotic  arsenic  cadmium  conjugating  degradation  downregulation  elevated  enzymes  family  hand  induce  inorganic  mercury  p53  promote  proteasomal  proximal  rat  suppressed  suppression  tubular  ubiquitin  ubiquitination 
Tagcloud (Difference) ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
accumulation  apoptosis  apoptotic  arsenic  cadmium  conjugating  degradation  downregulation  elevated  enzymes  family  hand  induce  inorganic  mercury  p53  promote  proteasomal  proximal  rat  suppressed  suppression  tubular  ubiquitin  ubiquitination 
Tagcloud (Intersection) ?