PIAS2 and CCHCR1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PIAS2	CCHCR1
Gene Name		protein inhibitor of activated STAT, 2	coiled-coil alpha-helical rod protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus PML Body Nuclear Speck	Nucleus Cytoplasm Centriole
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Androgen Receptor Binding SUMO Ligase Activity
	Biological Process	Transcription, DNA-templated Protein Sumoylation Androgen Receptor Signaling Pathway Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Androgen Receptor Signaling Pathway	Protein Export From Nucleus Multicellular Organismal Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Hematology traits ( 23263863) Nevirapine-induced rash ( 21810746) Prostate cancer ( 21743467) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) White blood cell count ( 21738480)
Protein-Protein Interactions		68 interactors: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CHMP4B CLDN2 CTBP1 DDX39B ELK1 ESR1 ESR2 FLI1 GFAP GFI1 GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 ITGB5 JUN MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 MYCN NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I ZBED1 ZBTB8A ZNF451	57 interactors: ABI2 ALAS1 AMOTL2 ATG5 BLOC1S6 C1orf94 CARD9 CCDC102B CCDC136 CCDC53 CDR2 CEP55 CTAGE5 DTNBP1 EFHC2 FSD2 GOLGA2 HAUS1 HSBP1 IKBKG KRT13 KRT15 KRT31 KRT40 MAD1L1 MED4 MID2 MTUS2 NAB2 NDC80 NDEL1 NINL NME7 NUP62 NUTM1 PIAS2 POLD2 POLR2C PRKCG RBM17 SAT1 SPAG5 SSX2IP STAR TADA2A TEKT1 TFIP11 TPM3 TRAF1 TRAF2 TRAF4 TRIM27 TSGA10 TXLNA TXLNB USHBP1 ZFYVE19
Entrez ID		9063	54535
HPRD ID		06944	05607
Ensembl ID		ENSG00000078043	ENSG00000204536
Uniprot IDs		O75928	B0S7V6 D2IYK9 M1T2K8 M1TIV4 Q2TB68 Q769H0 Q8TD31
PDB IDs		2ASQ 4FO9
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Transcription, DNA-templated Response To Organic Substance RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated RNA Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Protein Sumoylation Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cell Death Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Gland Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Protein Modification By Small Protein Conjugation Cellular Response To Lipid Macromolecule Biosynthetic Process Cellular Response To Stimulus Regulation Of Cellular Process Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Cellular Metabolic Process Cellular Response To Organic Cyclic Compound Regulation Of Cell Proliferation Regulation Of Signaling Signaling	Mitotic Cell Cycle Mitotic Cell Cycle Process Microtubule-based Transport Activation Of NF-kappaB-inducing Kinase Activity Cytoskeleton-dependent Intracellular Transport Organelle Organization Positive Regulation Of NIK/NF-kappaB Signaling Cell Cycle Process NIK/NF-kappaB Signaling Mitotic Nuclear Division Cell Cycle Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Microtubule-based Process Positive Regulation Of NF-kappaB Transcription Factor Activity Axon Cargo Transport Innate Immune Response Cell Division Positive Regulation Of Protein Homodimerization Activity Cytoskeleton Organization Microtubule-based Movement Establishment Of Organelle Localization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Release From Host Cell Establishment Of Vesicle Localization Intracellular Receptor Signaling Pathway Anterograde Synaptic Vesicle Transport Negative Regulation Of Neuron Death Vesicle Localization Regulation Of Protein Homodimerization Activity Centrosome Organization Negative Regulation Of Viral Transcription Melanosome Organization Establishment Of Localization In Cell Pigment Granule Organization Regulation Of Viral Release From Host Cell Regulation Of I-kappaB Kinase/NF-kappaB Signaling Developmental Process Organelle Localization Microtubule Organizing Center Organization Cellular Localization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Anterograde Axon Cargo Transport Regulation Of Apoptotic Process Microtubule Cytoskeleton Organization Positive Regulation Of JNK Cascade Spindle Organization Regulation Of Cell Death
Tagcloud ?		293t acts alphaclass androgen ar chaperone clone27 coimmunoprecipitation colocalization coregulator cytoplasm e3 factorkappab hek hela libraries ligase modulates prefoldintype sumoylation termed transcript transducer trapped twohybrid ubiquitously uxt yeast
Tagcloud (Difference) ?		293t acts alphaclass androgen ar chaperone clone27 coimmunoprecipitation colocalization coregulator cytoplasm e3 factorkappab hek hela libraries ligase modulates prefoldintype sumoylation termed transcript transducer trapped twohybrid ubiquitously uxt yeast
Tagcloud (Intersection) ?