HUWE1 and MCL1

  • Number of citations of the paper that reports this interaction (PMID 15989957)
  • 188
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

HUWE1

MCL1

Gene Name HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase myeloid cell leukemia 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: ABL1 CALM1 CCL1 CDKN2A HDAC2 LAPTM5 MCL1 MYC PIAS2 POLB RNF11 SMAD2 SMAD9 TP53 UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 29 interactors: BAD BAK1 BAX BBC3 BCL2L1 BCL2L11 BID BIK BMF BOK CASP3 DAD1 FBXW7 GSK3A GSK3B HRK HUWE1 MAPK1 MAPK10 PCNA PIN1 PMAIP1 TNKS TP53 TPT1 TRAF6 UHRF2 USP9X VDAC1
Entrez ID 10075 4170
HPRD ID 06608 08870
Ensembl ID ENSG00000086758 ENSG00000143384
Uniprot IDs Q7Z6Z7 C8YZ26 Q07820
PDB IDs 2EKK 3G1N 3H1D 2KBW 2NL9 2NLA 2PQK 3D7V 3IO9 3KJ0 3KJ1 3KJ2 3KZ0 3MK8 3PK1 3TWU 4HW2 4HW3 4HW4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
34a  bcl6  bim  btk  buffering  dlbcl  doi  fluctuations  follicular  foxp1  gab1  immunoglobulins  intimately  leu  lymphocytic  mantle  marginal  mirnas  modulators  myb  niches  preview  pu  put  stochastic  subtle  summarizing  tcl1  zap 
Tagcloud (Difference) ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
34a  bcl6  bim  btk  buffering  dlbcl  doi  fluctuations  follicular  foxp1  gab1  immunoglobulins  intimately  leu  lymphocytic  mantle  marginal  mirnas  modulators  myb  niches  preview  pu  put  stochastic  subtle  summarizing  tcl1  zap 
Tagcloud (Intersection) ?