HUWE1 and UBE2L3

  • Number of citations of the paper that reports this interaction (PMID 9575161)
  • 24

HUWE1

UBE2L3

Gene Name HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase ubiquitin-conjugating enzyme E2L 3
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: ABL1 CALM1 CCL1 CDKN2A HDAC2 LAPTM5 MCL1 MYC PIAS2 POLB RNF11 SMAD2 SMAD9 TP53 UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 64 interactors: ARIH1 ARIH2 ATXN3 BRCA1 CBL CBLC CCNB1IP1 CUL9 DTX3 FBXO2 FOS HACE1 HERC3 HSPA4 HUWE1 ITCH LIG4 MAPK6 MDM2 MID1 MKRN3 MUL1 NEDD4 NEDD4L NFKBIA NR3C1 PARK2 PJA1 POLR2A PTEN RAD23A RBCK1 RBX1 RELA RNF103 RNF113B RNF125 RNF144A RNF144B RNF19A RNF2 RNF216 SMAD4 SMAD7 SMURF1 SMURF2 STUB1 TRAF6 TRAF7 TRIM21 TRIM28 TRIM39 TRIP12 UBA1 UBA6 UBA7 UBASH3A UBC UBE3A UBE3C UBOX5 UBR5 WWP1 WWP2
Entrez ID 10075 7332
HPRD ID 06608 04762
Ensembl ID ENSG00000086758 ENSG00000185651
Uniprot IDs Q7Z6Z7 P68036
PDB IDs 2EKK 3G1N 3H1D 1C4Z 1FBV 3SQV 3SY2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e2  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
2e37a  2e37b  cav  cav2  channel  channels  clathrin  conjugating  conserved  dynamin  inhibiting  interact  internalization  involves  lc1  light  map1b  mechanism  microtubule  prevented  propose  proteasome  proteolytic  q  triggered  ubiquitin  ubiquitination  variants 
Tagcloud (Difference) ?
attractive  bicyclic  biol  catalyze  chem  cys  displacement  druggable  e3  freund  heclin  hect  heinis  hek293  huge  kills  ligase  ligases  makes  mule  nat  phage  proven  rutherford  smurf2  thioesters  winter  wwp1 
2e37a  2e37b  cav  cav2  channel  channels  clathrin  conjugating  conserved  dynamin  inhibiting  interact  internalization  involves  lc1  light  map1b  mechanism  microtubule  prevented  propose  proteasome  proteolytic  q  triggered  ubiquitin  ubiquitination  variants 
Tagcloud (Intersection) ?
e2