PIAS2 and SIAH1

  • Number of citations of the paper that reports this interaction (PMID 17533377)
  • 6
  • Data Source:
  • BioGRID (two hybrid)

PIAS2

SIAH1

Gene Name protein inhibitor of activated STAT, 2 siah E3 ubiquitin protein ligase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 68 interactors: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CHMP4B CLDN2 CTBP1 DDX39B ELK1 ESR1 ESR2 FLI1 GFAP GFI1 GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 ITGB5 JUN MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 MYCN NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I ZBED1 ZBTB8A ZNF451 135 interactors: AASDHPPT AFF1 AFF4 APC AQP1 ARMC9 ATN1 ATXN7 BAG1 BCL6 C14orf105 CACYBP CAPG CDC23 CDC34 CDK5R1 CTNNB1 DAB1 DCC DDX41 DNAJC15 DNALI1 EEF1D EIF3J ELL2 EXOC3-AS1 FAM90A1 FLI1 FZD9 GAPDH GDPD5 GRM5 HIPK2 HIPK3 HIST4H4 INHA KATNAL1 KCNJ10 KHDRBS3 KIAA0319L KIAA1217 KIAA1683 KIF1B KIF22 KIFC3 LACTB2 MAB21L1 MAPK12 MAPKBP1 MAPRE3 MOB3C MTIF3 MX1 MYD88 NELFA NOL6 NUMB NUMBL OPRM1 OTUB2 PEG10 PEG3 PFKM PHC1 PHC2 PIAS1 PIAS2 PIAS3 PKD1 POU2AF1 PRPF31 PRR20A PTPMT1 PUF60 PVRL2 PYGB QRICH1 RAB33A RAD51AP1 RAD54L2 RAPH1 RBBP8 RPL27A RPS19BP1 SDCBP SH3RF1 SLC9A3R2 SNCA SNCAIP SPATA4 SPATC1L STAT3 SYP SYT7 TBC1D22B TERF2 TFDP1 TMEM43 TNK2 TOLLIP TP53BP2 TRIM23 TRIM27 TRIM7 TRIM8 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 TXN UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2I UBE2K UBE2L6 UBE2N UBE2V2 UPP2 USP19 UXT VAV1 WDYHV1 ZBP1 ZCCHC10 ZCCHC13 ZFYVE21 ZMAT3 ZNF148 ZNF512B ZNF671
Entrez ID 9063 6477
HPRD ID 06944 03736
Ensembl ID ENSG00000078043 ENSG00000196470
Uniprot IDs O75928 Q8IUQ4
PDB IDs 2ASQ 4FO9 2A25 4I7B 4I7C 4I7D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
293t  acts  alphaclass  androgen  ar  chaperone  clone27  coimmunoprecipitation  colocalization  coregulator  cytoplasm  e3  factorkappab  hek  hela  libraries  ligase  modulates  prefoldintype  sumoylation  termed  transcript  transducer  trapped  twohybrid  ubiquitously  uxt  yeast 
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  e3  exerts  increases  inducing  inhibiting  introduce  ligase  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
Tagcloud (Difference) ?
293t  acts  alphaclass  androgen  ar  chaperone  clone27  coimmunoprecipitation  colocalization  coregulator  cytoplasm  factorkappab  hek  hela  libraries  modulates  prefoldintype  sumoylation  termed  transcript  transducer  trapped  twohybrid  ubiquitously  uxt  yeast 
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  exerts  increases  inducing  inhibiting  introduce  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
Tagcloud (Intersection) ?
e3  ligase