MATR3 and ERG

Number of citations of the paper that reports this interaction (PMID 24591637)
2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MATR3	ERG
Gene Name		matrin 3	v-ets avian erythroblastosis virus E26 oncogene homolog
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Inner Membrane Nucleoplasm Membrane Nuclear Matrix	Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Structural Molecule Activity Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Signal Transducer Activity Protein Binding Sequence-specific DNA Binding
	Biological Process		Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Signal Transduction Multicellular Organismal Development Cell Proliferation Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Metabolite levels (HVA) ( 23319000) Neonatal lupus ( 20662065) White blood cell types ( 21738478)
Protein-Protein Interactions		13 interactors: AIMP2 CALM1 DISC1 EGFR ERG GFI1B HNRNPK PCBP1 PTBP2 RASD1 SNAP23 TNFRSF21 TTF2	61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2
Entrez ID		9782	2078
HPRD ID		05270	01298
Ensembl ID		ENSG00000015479	ENSG00000157554
Uniprot IDs		B3KM87 B4DF66 P43243 Q9H4N1	B4DN83 B4DVX5 P11308
PDB IDs			1SXE 4IRG 4IRH 4IRI
Enriched GO Terms of Interacting Partners?		RNA Splicing Second-messenger-mediated Signaling MRNA Processing Gene Expression MRNA Metabolic Process Regulation Of Nitric-oxide Synthase Activity RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Metabolic Process Activation Of Phospholipase C Activity Cellular Response To Drug Negative Regulation Of Transmembrane Transport Positive Regulation Of Phospholipase C Activity Cell Proliferation Positive Regulation Of Transport Immune System Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Potassium Ion Export RNA Metabolic Process Regulation Of Cell Proliferation Regulation Of Oxidoreductase Activity Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Phospholipase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Positive Regulation Of Lipase Activity Cerebral Cortex Cell Migration Positive Regulation Of Protein Modification Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Pharynx Development Regulation Of Heart Rate By Hormone Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-5 Secretion Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Oligodendrocyte Apoptotic Process Astrocyte Activation Negative Regulation Of Transport Calcium-mediated Signaling Multicellular Organismal Development Hair Follicle Development Hair Cycle Process Negative Regulation Of Ion Transport	MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Metabolic Process Osteoblast Differentiation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Protein Refolding Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribosome Biogenesis Chromosome Organization Ossification Cis Assembly Of Pre-catalytic Spliceosome DNA Metabolic Process Regulation Of MRNA Stability Cell Differentiation Rhythmic Process Developmental Process Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process MRNA Stabilization Negative Regulation Of Transcription, DNA-templated Circadian Rhythm Ribonucleoprotein Complex Assembly
Tagcloud ?		3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?		3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?