MATR3 and PCBP1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MATR3	PCBP1
Gene Name		matrin 3	poly(rC) binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Inner Membrane Nucleoplasm Membrane Nuclear Matrix	Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Structural Molecule Activity Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process		MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AIMP2 CALM1 DISC1 EGFR ERG GFI1B HNRNPK PCBP1 PTBP2 RASD1 SNAP23 TNFRSF21 TTF2	36 interactors: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBM11 RBM42 SNRPA SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830
Entrez ID		9782	5093
HPRD ID		05270	03128
Ensembl ID		ENSG00000015479	ENSG00000169564
Uniprot IDs		B3KM87 B4DF66 P43243 Q9H4N1	Q15365 Q53SS8
PDB IDs			1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?		RNA Splicing Second-messenger-mediated Signaling MRNA Processing Gene Expression MRNA Metabolic Process Regulation Of Nitric-oxide Synthase Activity RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Metabolic Process Activation Of Phospholipase C Activity Cellular Response To Drug Negative Regulation Of Transmembrane Transport Positive Regulation Of Phospholipase C Activity Cell Proliferation Positive Regulation Of Transport Immune System Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Potassium Ion Export RNA Metabolic Process Regulation Of Cell Proliferation Regulation Of Oxidoreductase Activity Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Phospholipase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Positive Regulation Of Lipase Activity Cerebral Cortex Cell Migration Positive Regulation Of Protein Modification Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Pharynx Development Regulation Of Heart Rate By Hormone Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-5 Secretion Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Oligodendrocyte Apoptotic Process Astrocyte Activation Negative Regulation Of Transport Calcium-mediated Signaling Multicellular Organismal Development Hair Follicle Development Hair Cycle Process Negative Regulation Of Ion Transport	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cell Aging Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Macromolecule Biosynthetic Process Negative Regulation Of Potassium Ion Transmembrane Transport MRNA 3'-end Processing RNA Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Ventricular Cardiac Muscle Cell Action Potential RNA 3'-end Processing Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Translation Cellular Process Cardiac Muscle Cell Action Potential Involved In Contraction Biosynthetic Process MRNA Polyadenylation Positive Regulation Of RNA Splicing Cardiac Muscle Cell Action Potential RNA Polyadenylation
Tagcloud ?		3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd	atypical au element encoding eta half knockdown markedly owing pigmentosum polh poly prone rc responsive rich stability sufficient suppressor tls transcript translesion tumour uncovered upon utr variant xeroderma xpv
Tagcloud (Difference) ?		3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd	atypical au element encoding eta half knockdown markedly owing pigmentosum polh poly prone rc responsive rich stability sufficient suppressor tls transcript translesion tumour uncovered upon utr variant xeroderma xpv
Tagcloud (Intersection) ?