MATR3 and RASD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MATR3	RASD1
Description		matrin 3	ras related dexamethasone induced 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix	Nucleus Cytoplasm Plasma Membrane Membrane Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding G-protein Beta-subunit Binding
	Biological Process	Blastocyst Formation Activation Of Innate Immune Response Immune System Process Heart Valve Development Ventricular Septum Development Post-transcriptional Regulation Of Gene Expression Innate Immune Response	Signal Transduction G Protein-coupled Receptor Signaling Pathway Nitric Oxide Mediated Signal Transduction Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
GWAS		Body mass index ( 26426971) Malaria ( 31844061) Metabolite levels ( 23823483)	A body shape index ( 34021172) Chronotype ( 30696823) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		102 interacting genes: AIMP2 AKTIP CALM1 CDC42 EGFR ERG GFI1B HNRNPK HTR2B KRT27 KRT34 LINC01232 LMNA MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NRON PCBP1 PCBP3 PLEKHG4 PTBP2 PTEN RASD1 RNF10 SNAP23 SRPK2 TNFRSF21 TRAF1 TRAF6 TSGA10 TTF2 UBE2I USP7	38 interacting genes: ABI2 BHLHE41 CCDC57 CDR2L CYSRT1 EXOSC8 GNAI1 GNAI2 GNB1 HNRNPK HNRNPR KHDRBS3 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-9 KRTAP6-2 KRTAP6-3 MATR3 MDFI MKRN3 MTUS2 NBPF19 NOS1 NOS1AP NOTCH2NLA PLSCR1 PRDM5 PTPN21 RASAL3 RBMY1A1 RBMY1F RBMY1J TRIM37 WWP2
Entrez ID		9782	51655
HPRD ID		05270	08958
Ensembl ID		ENSG00000015479	ENSG00000108551
Uniprot IDs		A0A0R4J2E8 A8MXP9 B3KM87 B4DF66 P43243 Q9H4N1	Q9Y272
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Locomotion Negative Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of MRNA Metabolic Process Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Stability Regulation Of Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Translation Regulation Of RNA Stability Negative Regulation Of Developmental Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Negative Regulation Of Signal Transduction Regulation Of MRNA Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Extracellular Space Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Positive Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of MRNA Splicing, Via Spliceosome Heterotrimeric G-protein Complex Spliceosomal Complex Regulation Of RNA Splicing Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of RNA Splicing Regulation Of Membrane Repolarization During Action Potential Nucleic Acid Binding MRNA Metabolic Process MRNA Processing Guanyl Nucleotide Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of MRNA Metabolic Process Nucleolus Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Potassium Ion Transport Nitric Oxide Biosynthetic Process G-protein Beta/gamma-subunit Complex Binding Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization RNA Splicing Protein Binding
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