MATR3 and HNRNPK

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		MATR3	HNRNPK
Gene Name		matrin 3	heterogeneous nuclear ribonucleoprotein K
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Inner Membrane Nucleoplasm Membrane Nuclear Matrix	Nuclear Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Membrane Cell Projection Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Structural Molecule Activity Protein Binding Zinc Ion Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process		MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Processing Signal Transduction RNA Splicing Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Viral Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AIMP2 CALM1 DISC1 EGFR ERG GFI1B HNRNPK PCBP1 PTBP2 RASD1 SNAP23 TNFRSF21 TTF2	107 interactors: ABI2 APBB1 AQP5 BTRC C6orf226 CBLB CCAR1 CCDC33 CDKN1A CEBPB CIRBP CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 EIF3F ELAVL1 FBXL18 FYN GFI1B GRAP2 GRB2 GZMA GZMK HCK HIST3H3 HMGB1 HNRNPA0 HNRNPD HNRNPL HNRNPLL ITK ITSN2 KHDRBS1 KHDRBS2 KHDRBS3 LYN MAPK10 MARK4 MATR3 NCK2 NEDD4 NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PELI2 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 PTBP1 QKI RALY RASD1 RBFOX2 RBM10 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RNA18S5 RNA28S5 RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRRT SRSF3 SUMO1 SYNCRIP TBP TCERG1 TERF2IP TYK2 U2AF1 U2AF2 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF792 ZNRF2P1
Entrez ID		9782	3190
HPRD ID		05270	02834
Ensembl ID		ENSG00000015479	ENSG00000165119
Uniprot IDs		B3KM87 B4DF66 P43243 Q9H4N1	B4DFF1 B4DUQ1 P61978 Q6IBN1
PDB IDs			1J5K 1KHM 1ZZI 1ZZJ 1ZZK
Enriched GO Terms of Interacting Partners?		RNA Splicing Second-messenger-mediated Signaling MRNA Processing Gene Expression MRNA Metabolic Process Regulation Of Nitric-oxide Synthase Activity RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Metabolic Process Activation Of Phospholipase C Activity Cellular Response To Drug Negative Regulation Of Transmembrane Transport Positive Regulation Of Phospholipase C Activity Cell Proliferation Positive Regulation Of Transport Immune System Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Potassium Ion Export RNA Metabolic Process Regulation Of Cell Proliferation Regulation Of Oxidoreductase Activity Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Phospholipase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Positive Regulation Of Lipase Activity Cerebral Cortex Cell Migration Positive Regulation Of Protein Modification Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Pharynx Development Regulation Of Heart Rate By Hormone Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-5 Secretion Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Oligodendrocyte Apoptotic Process Astrocyte Activation Negative Regulation Of Transport Calcium-mediated Signaling Multicellular Organismal Development Hair Follicle Development Hair Cycle Process Negative Regulation Of Ion Transport	RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Immune Response Positive Regulation Of Metabolic Process MRNA Stabilization Innate Immune Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Metabolic Process Regulation Of Translation Negative Regulation Of Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Immune System Process Positive Regulation Of Gene Expression Regulation Of Immune System Process Defense Response Fc Receptor Signaling Pathway Positive Regulation Of Signal Transduction T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Difference) ?		3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Intersection) ?