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DZIP3 and TRIM21
Number of citations of the paper that reports this interaction (PMID
22493164
)
2
Data Source:
BioGRID
(two hybrid)
DZIP3
TRIM21
Gene Name
DAZ interacting zinc finger protein 3
tripartite motif containing 21
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoplasmic MRNA Processing Body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
SCF Ubiquitin Ligase Complex
Ribonucleoprotein Complex
Molecular Function
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Phosphatase Binding
Polyubiquitin Binding
Poly(A) RNA Binding
DNA Binding
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Identical Protein Binding
Biological Process
Protein Polyubiquitination
Protein Polyubiquitination
Protein Monoubiquitination
Cell Cycle
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Protein Destabilization
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Negative Regulation Of Viral Transcription
Innate Immune Response
Positive Regulation Of Cell Cycle
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Autoubiquitination
Interferon-gamma-mediated Signaling Pathway
Protein Trimerization
Negative Regulation Of Protein Deubiquitination
Negative Regulation Of Viral Release From Host Cell
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Interferon gamma signaling
Antigen processing: Ubiquitination & Proteasome degradation
Regulation of innate immune responses to cytosolic DNA
Cytosolic sensors of pathogen-associated DNA
STING mediated induction of host immune responses
Interferon Signaling
Cytokine Signaling in Immune system
Class I MHC mediated antigen processing & presentation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
42 interactors:
AKTIP
AP1M1
ARHGAP32
ATXN1
BIRC2
BIRC3
CEP63
DAZ1
GTF2H2C_2
HNRNPF
HNRNPUL1
HOTAIR
NCOR1
PCGF3
RAD18
RBM4B
RNF38
TOLLIP
TRIM21
TSG101
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2N
UBE2R2
UBE2U
UBE2V1
UBE2V2
UBE2W
UBE2Z
UBR3
ZCCHC10
ZNF24
ZNF765
37 interactors:
APC
CASP8AP2
CDC34
CUL1
DAXX
DCP2
DZIP3
FADD
FBXW11
GRAP
HLA-DRB1
IGHG1
IGHV4-31
IKBKB
IRF8
MNAT1
NIF3L1
RBCK1
RNF111
SKP2
TRIM27
TRIM39
TRIM5
TRIM8
TROVE2
TXN2
UBC
UBE2C
UBE2D1
UBE2D2
UBE2H
UBE2I
UBE2L3
USP15
USP2
USP4
YWHAZ
Entrez ID
9666
6737
HPRD ID
10562
00170
Ensembl ID
ENSG00000198919
ENSG00000132109
Uniprot IDs
Q86Y13
P19474
PDB IDs
2IWG
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Cellular Protein Modification Process
Cellular Macromolecule Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Protein K11-linked Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Toll-like Receptor Signaling Pathway
Proteasomal Protein Catabolic Process
Protein K63-linked Ubiquitination
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Cellular Protein Metabolic Process
Activation Of Innate Immune Response
Cellular Metabolic Process
Positive Regulation Of Innate Immune Response
TRIF-dependent Toll-like Receptor Signaling Pathway
Catabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Innate Immune Response
Protein Monoubiquitination
Proteolysis
Protein Metabolic Process
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Protein Ubiquitination
DNA Repair
Regulation Of Metabolic Process
Innate Immune Response
Immune Response-regulating Signaling Pathway
Regulation Of Protein Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Response To Stress
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Metabolic Process
Postreplication Repair
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Process
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Catabolic Process
Cellular Protein Modification Process
Proteolysis
Regulation Of Protein Ubiquitination
Protein Metabolic Process
Regulation Of Proteolysis
Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Signal Transduction
Mitotic Cell Cycle Process
Protein K48-linked Ubiquitination
Regulation Of Protein Metabolic Process
Cell Cycle
Cell Cycle Phase Transition
Regulation Of Protein Catabolic Process
Mitotic Cell Cycle
Innate Immune Response
Cell Cycle Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Stimulus
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cell Communication
Activation Of Innate Immune Response
Regulation Of Signaling
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Metabolic Process
Cell Surface Receptor Signaling Pathway
Mitotic Cell Cycle Phase Transition
Regulation Of Signal Transduction
Positive Regulation Of Ligase Activity
Response To Stimulus
Tagcloud
?
2ms
3ms
440ms
addressable
adjusting
albia
antibodies
bead
confounders
corrected
ekg
erythematosus
immunoassay
lupus
multicenter
prolongation
prolonged
qt
qtc
reasons
repolarization
resting
ro
ro52
ro60
separately
ss
ssc
univariate
Tagcloud (Difference)
?
2ms
3ms
440ms
addressable
adjusting
albia
antibodies
bead
confounders
corrected
ekg
erythematosus
immunoassay
lupus
multicenter
prolongation
prolonged
qt
qtc
reasons
repolarization
resting
ro
ro52
ro60
separately
ss
ssc
univariate
Tagcloud (Intersection)
?