DZIP3 and GTF2H2C_2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DZIP3	GTF2H2C_2
Description		DAZ interacting zinc finger protein 3	GTF2H2 family member C, copy 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Transcription Factor TFIIH Core Complex Nucleus Transcription Factor TFIIH Holo Complex Nuclear Speck
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	DNA Repair Nucleotide-excision Repair DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		53 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CCND1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	3 interacting genes: DZIP3 ERCC2 SUV39H1
Entrez ID		9666	730394
HPRD ID		10562	19238
Ensembl ID		ENSG00000198919
Uniprot IDs		Q86Y13	Q6P1K8
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Macromolecule Catabolic Process Protein Modification Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Protein Polyubiquitination Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Protein K11-linked Ubiquitination Transferase Activity Protein Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Macromolecule Metabolic Process UBC13-MMS2 Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Postreplication Repair Ubiquitin Conjugating Enzyme Complex Ubiquitin Protein Ligase Activity Nucleus Positive Regulation Of Post-translational Protein Modification Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Metabolic Process Catabolic Process Nucleoplasm Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding DNA Damage Response Positive Regulation Of Protein Metabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Macromolecule Metabolic Process DNA Repair Regulation Of RNA Metabolic Process	Determination Of Adult Lifespan RRNA Metabolic Process MMXD Complex CAK-ERCC2 Complex Transcription Elongation By RNA Polymerase I RRNA Processing Response To Hypoxia Regulation Of Mitotic Recombination Response To Oxygen Levels Hair Follicle Maturation Central Nervous System Myelin Formation Response To Decreased Oxygen Levels Positive Regulation Of Mitotic Recombination Histone H3K9 Trimethyltransferase Activity RDNA Heterochromatin Formation ENoSc Complex RDNA Heterochromatin 5'-3' DNA Helicase Activity Histone H3K9me2 Methyltransferase Activity Embryonic Cleavage Regulation Of Transcription By Glucose Regulation Of DNA Metabolic Process UV Protection Transcription Factor TFIIH Core Complex Transcription Factor TFIIH Holo Complex Transcription-coupled Nucleotide-excision Repair Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Nuclear Lamina Histone H3K9 Methyltransferase Activity Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei Chromatin Silencing Complex Myelin Assembly Erythrocyte Maturation Hematopoietic Stem Cell Differentiation Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Hair Cell Differentiation Histone H3 Methyltransferase Activity Hematopoietic Stem Cell Proliferation Blastocyst Hatching S-adenosylmethionine-dependent Methyltransferase Activity Spinal Cord Development Transcription Factor TFIID Complex DNA Damage Response Insulin-like Growth Factor Receptor Signaling Pathway Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity DNA Helicase Activity Polyubiquitin Modification-dependent Protein Binding Maturation Of SSU-rRNA
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