DZIP3 and AP1M1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DZIP3	AP1M1
Description		DAZ interacting zinc finger protein 3	adaptor related protein complex 1 subunit mu 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Golgi Membrane Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Plasma Membrane Membrane AP-1 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Specific Granule Membrane Synapse Extracellular Exosome
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Clathrin Adaptor Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Intracellular Protein Transport Protein Transport Vesicle-mediated Transport Melanosome Organization Endosome To Melanosome Transport Platelet Dense Granule Organization Melanosome Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)	Coronary artery disease ( 33020668)
Interacting Genes		53 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CCND1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	103 interacting genes: AMOT AP1M2 AP2B1 ARFRP1 ARL6IP4 ARNT2 ATF4 AXIN2 BACH2 BCAR3 BRCA1 C7orf57 CASP8 CCDC33 CEP57L1 CORO7 CTLA4 DCX DISC1 DVL2 DZIP3 EFEMP2 EHD2 ENTR1 ETV6 EVI5L FAM219B FAM9B FKBP7 FXR1 FXR2 GAK GCSAM GRIN2A GRIN2B HNRNPC HOOK1 HOOK2 IKZF1 KIF13A KIF24 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 LAMP1 LDOC1 LNX1 LRATD2 LRMDA LZTS1 LZTS2 MDK MEA1 MID2 MTF1 MYOD1 NECAB1 NKAP NKAPD1 OLIG3 PAX6 PHC2 PICK1 PIGR PNMA5 PURB RAPGEF3 ROPN1 RP9 RSPH14 RUNDC3A SDCBP2 SELP SLC2A4 SP4 SPATA6 SRPK2 SSX2IP TEPSIN TFIP11 TGOLN2 THAP6 TIFA TNIP1 TRIM27 TRIM41 UBC VAMP4 VANGL2 ZBTB14 ZBTB3 ZBTB43 ZBTB44 ZBTB8A ZCCHC17 ZNF19 ZNF219 ZNF276 ZNF552 ZNF655 ZNF8 ZSCAN16
Entrez ID		9666	8907
HPRD ID		10562	04639
Ensembl ID		ENSG00000198919	ENSG00000072958
Uniprot IDs		Q86Y13	B3KNH5 Q59EK3 Q9BXS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Macromolecule Catabolic Process Protein Modification Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Protein Polyubiquitination Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Protein K11-linked Ubiquitination Transferase Activity Protein Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Macromolecule Metabolic Process UBC13-MMS2 Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Postreplication Repair Ubiquitin Conjugating Enzyme Complex Ubiquitin Protein Ligase Activity Nucleus Positive Regulation Of Post-translational Protein Modification Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Metabolic Process Catabolic Process Nucleoplasm Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding DNA Damage Response Positive Regulation Of Protein Metabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Macromolecule Metabolic Process DNA Repair Regulation Of RNA Metabolic Process	Identical Protein Binding Protein Binding Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding Post-Golgi Vesicle-mediated Transport Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Domain Specific Binding Convergent Extension Involved In Neural Plate Elongation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Trans-Golgi Network Membrane Regulation Of Transcription By RNA Polymerase II Clathrin-coated Endocytic Vesicle Cellular Localization Intracellular Transport Developmental Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Synaptic Plasticity Negative Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Protein Complex Involved In Cell Adhesion Microtubule Convergent Extension Involved In Organogenesis Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion FHF Complex Regulation Of Neuronal Synaptic Plasticity Negative Regulation Of Regulatory T Cell Differentiation Convergent Extension Involved In Gastrulation Dentate Gyrus Development Protein Localization To Membrane Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity NMDA Glutamate Receptor Activity Regulation Of RNA Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?