DZIP3 and DAZ1

Number of citations of the paper that reports this interaction (PubMedID 12511597)
35

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DZIP3	DAZ1
Description		DAZ interacting zinc finger protein 3	deleted in azoospermia 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation 3'-UTR-mediated MRNA Stabilization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		53 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CCND1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	10 interacting genes: BOLL DAZAP1 DAZAP2 DAZL DYNLL1 DZIP1 DZIP1L DZIP3 PUM2 QKI
Entrez ID		9666	1617
HPRD ID		10562	15958
Ensembl ID		ENSG00000198919	ENSG00000188120
Uniprot IDs		Q86Y13	A0A140VJH5 Q9NQZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Macromolecule Catabolic Process Protein Modification Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Protein Polyubiquitination Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Protein K11-linked Ubiquitination Transferase Activity Protein Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Macromolecule Metabolic Process UBC13-MMS2 Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Postreplication Repair Ubiquitin Conjugating Enzyme Complex Ubiquitin Protein Ligase Activity Nucleus Positive Regulation Of Post-translational Protein Modification Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Metabolic Process Catabolic Process Nucleoplasm Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding DNA Damage Response Positive Regulation Of Protein Metabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Macromolecule Metabolic Process DNA Repair Regulation Of RNA Metabolic Process	MRNA 3'-UTR Binding Regulation Of MRNA Metabolic Process Organelle Assembly Stress Granule Assembly Regulation Of MRNA Stability Germ Cell Development Developmental Process Involved In Reproduction Regulation Of RNA Stability MRNA Stabilization Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of RNA Catabolic Process Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Translation Activator Activity Reproductive Process 3'-UTR-mediated MRNA Stabilization Regulation Of Translation Positive Regulation Of MRNA Metabolic Process RNA Binding Male Gamete Generation Spermatogenesis Organelle Organization Cytoplasm Gamete Generation MiRNA Binding Nucleic Acid Binding Post-transcriptional Regulation Of Gene Expression Motile Cilium Assembly Positive Regulation Of Translational Initiation Cilium Assembly Membraneless Organelle Assembly Cilium Organization Internal N(7)-methylguanine-containing RNA Reader Activity Protein Localization To Cilium Pumilio-response Element Binding Female Meiosis II Cell Development Negative Regulation Of Catabolic Process Cell Projection Assembly Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Cellular Component Assembly Plasma Membrane Bounded Cell Projection Assembly Myofibroblast Contraction Negative Regulation Of MiRNA Catabolic Process Smoothened Signaling Pathway BBSome Binding Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Sprouting Of Injured Axon Regulation Of Nucleobase-containing Compound Metabolic Process
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