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TRIM21 and NIF3L1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TRIM21
NIF3L1
Gene Name
tripartite motif containing 21
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic MRNA Processing Body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
SCF Ubiquitin Ligase Complex
Ribonucleoprotein Complex
Cytoplasm
Mitochondrion
Molecular Function
DNA Binding
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Identical Protein Binding
GTP Cyclohydrolase I Activity
Protein Binding
GTP Binding
Transcription Factor Binding
Metal Ion Binding
Biological Process
Protein Polyubiquitination
Protein Monoubiquitination
Cell Cycle
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Protein Destabilization
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Negative Regulation Of Viral Transcription
Innate Immune Response
Positive Regulation Of Cell Cycle
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Autoubiquitination
Interferon-gamma-mediated Signaling Pathway
Protein Trimerization
Negative Regulation Of Protein Deubiquitination
Negative Regulation Of Viral Release From Host Cell
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Pathways
Interferon gamma signaling
Antigen processing: Ubiquitination & Proteasome degradation
Regulation of innate immune responses to cytosolic DNA
Cytosolic sensors of pathogen-associated DNA
STING mediated induction of host immune responses
Interferon Signaling
Cytokine Signaling in Immune system
Class I MHC mediated antigen processing & presentation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
APC
CASP8AP2
CDC34
CUL1
DAXX
DCP2
DZIP3
FADD
FBXW11
GRAP
HLA-DRB1
IGHG1
IGHV4-31
IKBKB
IRF8
MNAT1
NIF3L1
RBCK1
RNF111
SKP2
TRIM27
TRIM39
TRIM5
TRIM8
TROVE2
TXN2
UBC
UBE2C
UBE2D1
UBE2D2
UBE2H
UBE2I
UBE2L3
USP15
USP2
USP4
YWHAZ
64 interactors:
AP5B1
APIP
ARPIN
BEND7
CCDC102B
CCDC85B
CDKN2B
CDKN2C
COIL
COPS2
CUTC
DCDC2
DCTD
DCTPP1
DHPS
DMC1
DMRTB1
DUSP23
DYNLT3
EIF5A2
ENOX1
EPHB6
FAM49B
FXR2
GNMT
GRB2
KCTD17
KRT15
KXD1
LAMTOR3
LMO2
MAGEA11
MAPRE2
MLXIPL
NATD1
NME1
NOL3
NUDT14
NUDT21
ORC5
PAICS
PCBD1
PRTFDC1
RABAC1
RAD54B
RPIA
S100A1
SAT1
SNF8
STAT3
STK16
SULT1A2
SULT1A3
SYT17
THOC7
TIFA
TRAF2
TRIM21
TRIP13
TSC22D4
VIM
YES1
YWHAQ
ZBED1
Entrez ID
6737
60491
HPRD ID
00170
10424
Ensembl ID
ENSG00000132109
ENSG00000196290
Uniprot IDs
P19474
Q9GZT8
PDB IDs
2IWG
Enriched GO Terms of Interacting Partners
?
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Catabolic Process
Cellular Protein Modification Process
Proteolysis
Regulation Of Protein Ubiquitination
Protein Metabolic Process
Regulation Of Proteolysis
Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Signal Transduction
Mitotic Cell Cycle Process
Protein K48-linked Ubiquitination
Regulation Of Protein Metabolic Process
Cell Cycle
Cell Cycle Phase Transition
Regulation Of Protein Catabolic Process
Mitotic Cell Cycle
Innate Immune Response
Cell Cycle Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Stimulus
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cell Communication
Activation Of Innate Immune Response
Regulation Of Signaling
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Metabolic Process
Cell Surface Receptor Signaling Pathway
Mitotic Cell Cycle Phase Transition
Regulation Of Signal Transduction
Positive Regulation Of Ligase Activity
Response To Stimulus
Protein Oligomerization
Nucleobase-containing Compound Metabolic Process
Protein Tetramerization
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Nitrogen Compound Metabolic Process
Nucleoside Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Protein Complex Assembly
Protein Homotetramerization
Purine Nucleoside Metabolic Process
Protein Homooligomerization
Peptidyl-lysine Modification To Peptidyl-hypusine
Polyamine Metabolic Process
Polyamine Catabolic Process
Ribose Phosphate Metabolic Process
Reciprocal Meiotic Recombination
Nucleotide Metabolic Process
Amine Metabolic Process
Ribonucleotide Metabolic Process
Biosynthetic Process
Cellular Metabolic Process
Purine Nucleotide Metabolic Process
S-adenosylmethionine Metabolic Process
Methionine Metabolic Process
Regulation Of Protein Homodimerization Activity
Cellular Component Assembly
Sulfation
Sulfur Compound Metabolic Process
Positive Regulation Of T Cell Activation
Gene Expression
Amine Biosynthetic Process
Oocyte Maturation
Positive Regulation Of Homotypic Cell-cell Adhesion
Transcription, DNA-templated
Regulation Of Glycolytic Process
Meiosis I
Organophosphate Metabolic Process
Male Meiosis I
Cell Cycle Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cell-cell Adhesion
RNA Biosynthetic Process
Response To Injury Involved In Regulation Of Muscle Adaptation
Deoxyhypusine Biosynthetic Process From Spermidine
Glucose Mediated Signaling Pathway
Polyamine Homeostasis
Response To Brefeldin A
Tagcloud
?
2ms
3ms
440ms
addressable
adjusting
albia
antibodies
bead
confounders
corrected
ekg
erythematosus
immunoassay
lupus
multicenter
prolongation
prolonged
qt
qtc
reasons
repolarization
resting
ro
ro52
ro60
separately
ss
ssc
univariate
Tagcloud (Difference)
?
2ms
3ms
440ms
addressable
adjusting
albia
antibodies
bead
confounders
corrected
ekg
erythematosus
immunoassay
lupus
multicenter
prolongation
prolonged
qt
qtc
reasons
repolarization
resting
ro
ro52
ro60
separately
ss
ssc
univariate
Tagcloud (Intersection)
?