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DZIP3 and NCOR1
Number of citations of the paper that reports this interaction (PubMedID
18206970
)
64
Data Source:
HPRD
(in vivo)
DZIP3
NCOR1
Description
DAZ interacting zinc finger protein 3
nuclear receptor corepressor 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Histone Deacetylase Complex
Chromatin
Nucleus
Nucleoplasm
Cytosol
Membrane
Transcription Repressor Complex
Mitotic Spindle
Molecular Function
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Phosphatase Binding
Polyubiquitin Modification-dependent Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Transcription Cis-regulatory Region Binding
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Binding
Histone Deacetylase Binding
Nuclear Thyroid Hormone Receptor Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Biological Process
Protein Polyubiquitination
Protein Ubiquitination
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Regulation Of Ketone Metabolic Process
Locomotor Rhythm
Negative Regulation Of Glycolytic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of JNK Cascade
Rhythmic Process
Spindle Assembly
Negative Regulation Of Androgen Receptor Signaling Pathway
Negative Regulation Of MiRNA Transcription
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Nuclear signaling by ERBB4
Nuclear signaling by ERBB4
PPARA activates gene expression
PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HDACs deacetylate histones
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by PPARalpha
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
Cytoprotection by HMOX1
Heme signaling
Heme signaling
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Expression of BMAL (ARNTL), CLOCK, and NPAS2
Expression of BMAL (ARNTL), CLOCK, and NPAS2
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
Drugs
Diseases
GWAS
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
27863252
)
Adult body size (
32376654
)
C-reactive protein levels (
30388399
)
FEV1 (
30804560
)
Free thyroxine concentration (
30367059
)
Lung function (FEV1) (
26635082
)
Lung function (FVC) (
30804560
)
Lymphocyte count (
32888494
)
Interacting Genes
53 interacting genes:
AKTIP
AP1M1
ARHGAP32
ATXN1
BAG4
BIRC2
BIRC3
CARM1
CCND1
CEP63
DAZ1
FBXO17
GRIP1
GTF2H2C_2
HNRNPF
HNRNPH1
HNRNPUL1
HOTAIR
HOXC8
MIR20A
MIR29C
NCOR1
PCGF3
PITX1
RAD18
RBM4B
RNF38
RUNX1
TNS2
TOLLIP
TRIM21
TSG101
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2N
UBE2R2
UBE2U
UBE2V1
UBE2V2
UBE2W
UBE2Z
UBR3
ZCCHC10
ZNF24
ZNF765
98 interacting genes:
ACTN2
AR
ATXN1
ATXN1L
ATXN3
BCL6
C1D
CBFA2T2
CHD1
CHUK
CLK1
CNOT2
COPS2
CSNK2A1
CXADR
DACH1
DDX20
DHX30
DZIP3
ENO1
ESR1
ESR2
ETS1
ETS2
GABARAP
GABARAPL1
GABARAPL2
GPS2
GTF2B
H3C1
H4C1
HDAC3
HDAC5
HDAC9
HESX1
HEY2
HTT
KLF5
MAP1LC3A
MAP1LC3B
MAP1LC3C
MECP2
MYB
MYBL2
MYOD1
NCOA1
NCOA3
NCOR2
NELFE
NR1D1
NR1D2
NR1H2
NR1H3
NR2E3
NR3C1
NR6A1
OVOL2
PDCD2
PHB1
PIAS1
PML
POU1F1
PPARA
PPARD
PPARG
PTMA
PTOV1
RARA
RARG
RBPJ
RUNX1
RUNX1T1
RXRA
SAFB
SAP30
SKI
SKIL
SNW1
SP1
SPEN
SQSTM1
SUMO2
TAB2
TAF6
TAF9
TBL1X
TBL1XR1
THRA
THRB
TRIM14
TULP3
TXNRD2
VDR
ZBTB16
ZBTB33
ZBTB5
ZBTB7A
ZMYND11
Entrez ID
9666
9611
HPRD ID
10562
02911
Ensembl ID
ENSG00000198919
ENSG00000141027
Uniprot IDs
Q86Y13
A0A994J5B8
H0Y459
O75376
Q6PGR4
PDB IDs
2EQR
3H52
3KMZ
3N00
4MDD
4WVD
6ONI
6WMQ
6WMS
6XXS
6XYX
6XZZ
6Y17
6ZBU
8AS9
8D8I
8DKN
8DKV
8FHE
8FHG
8FKC
8FKD
8FKE
8FKF
8FKG
Enriched GO Terms of Interacting Partners
?
Ubiquitin Conjugating Enzyme Activity
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Ubiquitin-protein Transferase Activity
Post-translational Protein Modification
Proteolysis Involved In Protein Catabolic Process
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Monoubiquitination
Macromolecule Catabolic Process
Protein Modification Process
Protein K63-linked Ubiquitination
Proteolysis
Regulation Of Protein Polyubiquitination
Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein Polyubiquitination
Protein K11-linked Ubiquitination
Transferase Activity
Protein Metabolic Process
Positive Regulation Of Protein K63-linked Ubiquitination
Macromolecule Metabolic Process
UBC13-MMS2 Complex
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Post-translational Protein Modification
Regulation Of Protein Modification Process
Regulation Of Protein Metabolic Process
Postreplication Repair
Ubiquitin Conjugating Enzyme Complex
Ubiquitin Protein Ligase Activity
Nucleus
Positive Regulation Of Post-translational Protein Modification
Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Metabolic Process
Catabolic Process
Nucleoplasm
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Ubiquitination
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
ATP Binding
DNA Damage Response
Positive Regulation Of Protein Metabolic Process
Error-free Postreplication DNA Repair
Negative Regulation Of Macromolecule Metabolic Process
DNA Repair
Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA Binding
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Nuclear Receptor Activity
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Receptor-mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Regulation Of Metabolic Process
Nucleus
Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Intracellular Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
DNA-binding Transcription Factor Activity
Positive Regulation Of Metabolic Process
DNA-templated Transcription
Chromatin
Transcription By RNA Polymerase II
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Retinoic Acid Receptor Signaling Pathway
Transcription Repressor Complex
Cell Differentiation
Transcription Corepressor Activity
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Cellular Developmental Process
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
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