DZIP3 and ARHGAP32

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DZIP3	ARHGAP32
Gene Name		DAZ interacting zinc finger protein 3	Rho GTPase activating protein 32
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Cell Junction Dendritic Spine Postsynaptic Membrane
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Phosphatase Binding Polyubiquitin Binding Poly(A) RNA Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol Binding
	Biological Process	Protein Polyubiquitination	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS			Metabolite levels (5-HIAA) ( 23319000)
Protein-Protein Interactions		42 interactors: AKTIP AP1M1 ARHGAP32 ATXN1 BIRC2 BIRC3 CEP63 DAZ1 GTF2H2C_2 HNRNPF HNRNPUL1 HOTAIR NCOR1 PCGF3 RAD18 RBM4B RNF38 TOLLIP TRIM21 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	34 interactors: ABI2 AES AKT1 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LZTS2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC
Entrez ID		9666	9743
HPRD ID		10562	12257
Ensembl ID		ENSG00000198919	ENSG00000134909
Uniprot IDs		Q86Y13	A7KAX9 I7H0B0 Q86T64
PDB IDs			3IUG
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Metabolic Process Activation Of Innate Immune Response Cellular Metabolic Process Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Protein Monoubiquitination Proteolysis Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Protein Ubiquitination DNA Repair Regulation Of Metabolic Process Innate Immune Response Immune Response-regulating Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Stress Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Postreplication Repair Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction System Development Positive Regulation Of Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Locomotion ERBB Signaling Pathway Multicellular Organismal Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Anatomical Structure Development Fc Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Developmental Process Immune Response-regulating Signaling Pathway Signaling Neurogenesis Cell Communication Cell Migration Signal Transduction Regulation Of Phosphorus Metabolic Process Axon Guidance Cell Activation Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Cell Development Cell Surface Receptor Signaling Pathway Cell Motility Neuron Differentiation Cell Projection Organization Cellular Response To Organonitrogen Compound Neuron Development Chemotaxis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Nervous System Development Organ Development Neuron Projection Development Cell Differentiation Regulation Of Cell-cell Adhesion
Tagcloud ?			10kb appbp2 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?			10kb appbp2 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?