DZIP3 and MIR20A

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		DZIP3	MIR20A
Description		DAZ interacting zinc finger protein 3	microRNA 20a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Space RISC Complex Extracellular Vesicle
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Negative Regulation Of Cytokine-mediated Signaling Pathway Outflow Tract Morphogenesis Inflammatory Response Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Interleukin-17 Production Negative Regulation Of Toll-like Receptor 4 Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Cellular Response To Hypoxia Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Cardioblast Proliferation Positive Regulation Of Pulmonary Blood Vessel Remodeling
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		53 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CCND1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	73 interacting genes: AIMP2 APOBEC3B C1QBP CRTAP DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		9666	406982
HPRD ID		10562
Ensembl ID		ENSG00000198919	ENSG00000283762
Uniprot IDs		Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Macromolecule Catabolic Process Protein Modification Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Protein Polyubiquitination Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Protein K11-linked Ubiquitination Transferase Activity Protein Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Macromolecule Metabolic Process UBC13-MMS2 Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Postreplication Repair Ubiquitin Conjugating Enzyme Complex Ubiquitin Protein Ligase Activity Nucleus Positive Regulation Of Post-translational Protein Modification Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Metabolic Process Catabolic Process Nucleoplasm Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding DNA Damage Response Positive Regulation Of Protein Metabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Macromolecule Metabolic Process DNA Repair Regulation Of RNA Metabolic Process	RNA Binding Nucleic Acid Binding RNA Processing RNA Splicing RNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome Nucleus RNA Splicing, Via Transesterification Reactions Macromolecule Metabolic Process Nucleoplasm Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex Catalytic Step 2 Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Translation MRNA 3'-UTR Binding Regulation Of MRNA Processing Negative Regulation Of MRNA Metabolic Process MiRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Positive Regulation Of Cytoplasmic Translation Regulation Of Metabolic Process Negative Regulation Of Translation MRNA Stabilization Positive Regulation Of Gene Expression Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of RNA Stability Nucleolus Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process P-body Positive Regulation Of Biosynthetic Process
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