SIAH1 and UBE2E3

  • Number of citations of the paper that reports this interaction (PMID 11389839)
  • 132
  • Data Source:
  • BioGRID (two hybrid)

SIAH1

UBE2E3

Gene Name siah E3 ubiquitin protein ligase 1 ubiquitin-conjugating enzyme E2E 3
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 135 interactors: AASDHPPT AFF1 AFF4 APC AQP1 ARMC9 ATN1 ATXN7 BAG1 BCL6 C14orf105 CACYBP CAPG CDC23 CDC34 CDK5R1 CTNNB1 DAB1 DCC DDX41 DNAJC15 DNALI1 EEF1D EIF3J ELL2 EXOC3-AS1 FAM90A1 FLI1 FZD9 GAPDH GDPD5 GRM5 HIPK2 HIPK3 HIST4H4 INHA KATNAL1 KCNJ10 KHDRBS3 KIAA0319L KIAA1217 KIAA1683 KIF1B KIF22 KIFC3 LACTB2 MAB21L1 MAPK12 MAPKBP1 MAPRE3 MOB3C MTIF3 MX1 MYD88 NELFA NOL6 NUMB NUMBL OPRM1 OTUB2 PEG10 PEG3 PFKM PHC1 PHC2 PIAS1 PIAS2 PIAS3 PKD1 POU2AF1 PRPF31 PRR20A PTPMT1 PUF60 PVRL2 PYGB QRICH1 RAB33A RAD51AP1 RAD54L2 RAPH1 RBBP8 RPL27A RPS19BP1 SDCBP SH3RF1 SLC9A3R2 SNCA SNCAIP SPATA4 SPATC1L STAT3 SYP SYT7 TBC1D22B TERF2 TFDP1 TMEM43 TNK2 TOLLIP TP53BP2 TRIM23 TRIM27 TRIM7 TRIM8 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 TXN UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2I UBE2K UBE2L6 UBE2N UBE2V2 UPP2 USP19 UXT VAV1 WDYHV1 ZBP1 ZCCHC10 ZCCHC13 ZFYVE21 ZMAT3 ZNF148 ZNF512B ZNF671 75 interactors: ACVR1 ARID3A ARIH2 ATXN1 BARD1 BRCA1 CADPS2 CHFR CHUK CNOT4 CUL1 CUL3 CUL4A DTX3 DTX3L DZIP3 HERC4 HTT IPO11 ITCH KLHL42 MARCH5 MDM2 MID1 MID2 MKRN3 MUL1 NEDD4L NFKBIA RBX1 RCBTB1 RCBTB2 RFWD3 RING1 RMND5B RNF10 RNF11 RNF111 RNF114 RNF115 RNF13 RNF130 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF25 RNF4 RNF43 RNF5 RNF8 SAE1 SIAH1 SPOP STUB1 TGFBR1 TRIM2 TRIM27 TRIM32 TRIM37 TRIM38 TRIM39 TRIM45 TRIM50 UBA1 UBC UBOX5 UFM1 WWP2 ZNRF1 ZNRF4
Entrez ID 6477 10477
HPRD ID 03736 05000
Ensembl ID ENSG00000196470 ENSG00000170035
Uniprot IDs Q8IUQ4 Q969T4
PDB IDs 2A25 4I7B 4I7C 4I7D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  e3  exerts  increases  inducing  inhibiting  introduce  ligase  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
conjugating  cytoprotective  degraded  extracting  govern  homeostasis  imp  import  importin  keap1  locales  localizes  mitochondria  nrf2  outer  p45  partitioning  perinuclear  prematurely  relocalizes  repressive  restore  restrict  restricting  subcellular  tightly  transcriptionally  unresolved 
Tagcloud (Difference) ?
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  e3  exerts  increases  inducing  inhibiting  introduce  ligase  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
conjugating  cytoprotective  degraded  extracting  govern  homeostasis  imp  import  importin  keap1  locales  localizes  mitochondria  nrf2  outer  p45  partitioning  perinuclear  prematurely  relocalizes  repressive  restore  restrict  restricting  subcellular  tightly  transcriptionally  unresolved 
Tagcloud (Intersection) ?