GORASP2 and RGS3

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		GORASP2	RGS3
Description		golgi reassembly stacking protein 2	regulator of G protein signaling 3
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cis-Golgi Network Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Response To Unfolded Protein Organelle Organization Golgi Organization Spermatogenesis Cell Differentiation Response To Endoplasmic Reticulum Stress Establishment Of Protein Localization To Plasma Membrane Organelle Assembly	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization	G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Autism spectrum disorder ( 34069769) Cognitive performance ( 19734545)	Height ( 28552196) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		144 interacting genes: - AAMDC ACY3 ALKBH4 APIP APP ARHGEF15 ARL6IP1 ASMTL ATP6V1G1 ATXN1L BEND5 BLZF1 BTBD3 C1orf94 C21orf91 CARHSP1 CBLB CBY1 CCDC90B CDA CDC23 CDK18 CDKN2D CEP76 CGGBP1 CHMP1A CNTNAP2 CRYAA CRYAB DCTD DMC1 DNAJB13 DPYSL2 DRC12 DUSP21 DUSP4 DYRK3 ECHDC1 EIF2B1 EMILIN3 ENOX1 ENOX2 ETHE1 FIG4 GABPB2 GNG7 GNGT1 GOLGA2 GOLGA6L2 GRIK1 GSTZ1 GTF2IRD1 HOXC5 HSBP1 IFT25 JADE2 KCTD13 KCTD5 KCTD7 KCTD9 KIFC3 KRTAP5-11 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MATN4 MID2 MIEN1 MIF MORN2 MPLKIP MSC MYOM3 NCOA5 NHSL2 NME1 NMNAT1 NQO2 NUDT5 NUP62 ODC1 OGT PCBD1 PDE9A PNMA5 PRDX3 PRKAB2 PRPS1 PRRC2A PSMA3 PSMD6 RAB1A RAB27B RAB2A RAB39A RAD54B RBM46 REEP6 RGL2 RGS3 RPIA RPS6KA1 SCAND1 SELENBP1 SEPTIN1 SEPTIN14 SHMT1 STOX1 TAGLN TCF4 TEKT3 TGFA TLE5 TMED2 TMED3 TP53RK TPH1 TRAF1 TRAF2 TRAF4 TRAF5 TRAPPC6A TRIM38 TRPT1 TSC22D1 TSC22D4 TSEN15 TSN TTC19 TXLNA UBE2Z UBL3 VPS37B VPS52 XPNPEP1 ZBED1 ZBTB14 ZMAT1 ZMYND19 ZNF148	24 interacting genes: ACD APP CNKSR2 CYSRT1 DEPDC1B EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PAX6 PLSCR1 PRKN SCN5A YWHAB YWHAE YWHAQ YWHAZ
Entrez ID		26003	5998
HPRD ID		08303	03720
Ensembl ID		ENSG00000115806	ENSG00000138835
Uniprot IDs		Q9H8Y8	A0A087WUY2 A0A8Q3WKG2 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3
PDB IDs		3RLE 4EDJ	2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Cytosol Thioesterase Binding Pyrimidine-containing Compound Metabolic Process Protein Homooligomerization Cytoplasm Pyrimidine Nucleotide Biosynthetic Process Protein Complex Oligomerization Pyrimidine-containing Compound Biosynthetic Process Stress-activated MAPK Cascade Protein-containing Complex Organization Pyrimidine Nucleotide Metabolic Process Stress-activated Protein Kinase Signaling Cascade Cytosine Metabolic Process Golgi Organization Ultradian Rhythm Regulation Of Programmed Cell Death Protein-containing Complex Assembly Tumor Necrosis Factor Receptor Binding PTB Domain Binding Negative Regulation Of Programmed Cell Death D-ribose Metabolic Process MAP Kinase Activity Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process DTMP Biosynthetic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process ATP Generation From Poly-ADP-D-ribose Nucleoside Monophosphate Biosynthetic Process	Phosphoserine Residue Binding Enzyme Binding G Protein-coupled Receptor Binding Ephrin Receptor Binding Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Process Protein Domain Specific Binding Regulation Of Spontaneous Synaptic Transmission Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Membrane Potential Ligand-gated Ion Channel Signaling Pathway Protein Sequestering Activity Signal Transduction Regulation Of Transport Protein Kinase Binding Negative Regulation Of Protein Localization To Nucleus Transmembrane Transporter Binding Modulation Of Excitatory Postsynaptic Potential Regulation Of Monoatomic Ion Transmembrane Transport Peptidase Activator Activity System Development Cellular Response To Manganese Ion Extracellular Exosome Ubiquitin Protein Ligase Binding Regulation Of Establishment Of Protein Localization Glutamatergic Synapse Regulation Of MiRNA Transcription Response To Manganese Ion Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Targeting Regulation Of Protein Localization Negative Regulation Of Protein Localization Response To Lead Ion Negative Regulation Of RNA Biosynthetic Process Regulation Of Monoatomic Ion Transport Regulation Of MiRNA Metabolic Process Negative Regulation Of DNA-templated Transcription Cellular Response To Catecholamine Stimulus Regulation Of Protein Transport Regulation Of Neurotransmitter Uptake Response To Catecholamine Focal Adhesion Guanyl Nucleotide Binding Startle Response Negative Regulation Of Transport Regulation Of Innate Immune Response Positive Regulation Of Protein Transport Melanosome Negative Regulation Of Macromolecule Metabolic Process G-protein Beta/gamma-subunit Complex Binding
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