GORASP2 and PDE9A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GORASP2	PDE9A
Gene Name		golgi reassembly stacking protein 2, 55kDa	phosphodiesterase 9A
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Mitotic Cell Cycle Organelle Organization	Signal Transduction Blood Coagulation Metabolic Process CGMP-mediated Signaling
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase	Platelet homeostasis Nitric oxide stimulates guanylate cyclase cGMP effects
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		69 interactors: AAMDC ACY3 AES APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148	18 interactors: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NL PHYHIPL SULT1E1 TRIM32 TRPV6 UTP23
Entrez ID		26003	5152
HPRD ID		08303	09115
Ensembl ID		ENSG00000115806	ENSG00000160191
Uniprot IDs		B4DKT0 B4DNR1 Q9H8Y8	O76083
PDB IDs		3RLE 4EDJ	2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Golgi Organization Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of MAP Kinase Activity Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cargo Loading Into Vesicle Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Protein Transport Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Establishment Of Protein Localization Intracellular Protein Transport Regulation Of Protein Homodimerization Activity Regulation Of MAPK Cascade TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway COPII-coated Vesicle Budding Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor 3 Signaling Pathway Establishment Of Localization In Cell Regulation Of Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Protein Complex Assembly Positive Regulation Of Protein Metabolic Process Protein Homooligomerization Toll-like Receptor 4 Signaling Pathway Cell Death Death Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Positive Regulation Of Transferase Activity Cellular Localization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Protein Ubiquitination Intracellular Transport Negative Regulation Of Programmed Cell Death Negative Regulation Of Transferase Activity Protein Oligomerization Endomembrane System Organization Cell Cycle Cellular Protein Localization
Tagcloud ?			acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576
Tagcloud (Difference) ?			acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576
Tagcloud (Intersection) ?