GORASP2 and DUSP21

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GORASP2	DUSP21
Gene Name		golgi reassembly stacking protein 2, 55kDa	dual specificity phosphatase 21
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Nucleus Cytoplasm Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Protein Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Mitotic Cell Cycle Organelle Organization	Inactivation Of MAPK Activity Peptidyl-tyrosine Dephosphorylation
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		69 interactors: AAMDC ACY3 AES APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148	4 interactors: APP GORASP2 RGS2 TEX11
Entrez ID		26003	63904
HPRD ID		08303	06494
Ensembl ID		ENSG00000115806	ENSG00000189037
Uniprot IDs		B4DKT0 B4DNR1 Q9H8Y8	Q9H596
PDB IDs		3RLE 4EDJ
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Golgi Organization Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of MAP Kinase Activity Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cargo Loading Into Vesicle Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Protein Transport Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Establishment Of Protein Localization Intracellular Protein Transport Regulation Of Protein Homodimerization Activity Regulation Of MAPK Cascade TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway COPII-coated Vesicle Budding Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor 3 Signaling Pathway Establishment Of Localization In Cell Regulation Of Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Protein Complex Assembly Positive Regulation Of Protein Metabolic Process Protein Homooligomerization Toll-like Receptor 4 Signaling Pathway Cell Death Death Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Positive Regulation Of Transferase Activity Cellular Localization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Protein Ubiquitination Intracellular Transport Negative Regulation Of Programmed Cell Death Negative Regulation Of Transferase Activity Protein Oligomerization Endomembrane System Organization Cell Cycle Cellular Protein Localization	Sexual Reproduction Synaptic Growth At Neuromuscular Junction Reproduction Collateral Sprouting In Absence Of Injury Meiotic Gene Conversion Reproductive Process Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Translation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Meiosis Chromosome Segregation Regulation Of Adrenergic Receptor Signaling Pathway Axon Choice Point Recognition Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Chiasma Assembly Neuron Remodeling Relaxation Of Vascular Smooth Muscle Relaxation Of Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Hydrolase Activity Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Microtubule Polymerization Resolution Of Meiotic Recombination Intermediates Relaxation Of Cardiac Muscle Negative Regulation Of Smooth Muscle Contraction Cellular Copper Ion Homeostasis Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Chromosome Separation Copper Ion Homeostasis Suckling Behavior Synaptonemal Complex Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Synaptonemal Complex Organization Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cardiac Muscle Hypertrophy Regulation Of Protein Kinase Activity Mating Behavior Vasodilation
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