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ACTL6A and EWSR1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
ACTL6A
EWSR1
Gene Name
actin-like 6A
EWS RNA-binding protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Plasma Membrane
SWI/SNF Complex
Ino80 Complex
NuA4 Histone Acetyltransferase Complex
Protein Complex
NpBAF Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Plasma Membrane
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
Chromatin Binding
Transcription Coactivator Activity
Protein Binding
Nucleosomal DNA Binding
Nucleotide Binding
RNA Binding
Protein Binding
Calmodulin Binding
Zinc Ion Binding
Identical Protein Binding
Poly(A) RNA Binding
Biological Process
Neural Retina Development
DNA Repair
DNA Recombination
Chromatin Organization
Chromatin Remodeling
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Signal Transduction
Nervous System Development
Regulation Of Growth
ATP-dependent Chromatin Remodeling
Histone H4 Acetylation
Histone H2A Acetylation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Breast cancer (
23535729
)
Protein-Protein Interactions
13 interactors:
ARHGDIA
CDK2
CDK9
EWSR1
FLII
MRGBP
MYC
POLR2A
RELA
RUVBL1
SMARCA2
SMARCA4
TRRAP
159 interactors:
ACTL6A
AGT
ATN1
ATPAF2
ATXN3
BAD
BARD1
BLZF1
BNIP3L
BTK
C10orf12
C11orf16
C19orf57
CALM1
CCDC91
CD177
CDK12
CEACAM5
CETP
CFDP1
CHERP
CNST
CPSF6
CPSF7
CREBBP
CUEDC2
CXADR
DFFA
DHX9
DMRTB1
DNAJB3
DYNLL2
E2F8
ECD
ELAVL3
ELAVL4
ELK1
EP300
EPAS1
EPT1
ERCC5
FAM131C
FASN
FLI1
FUS
FXR2
GNPDA1
GPBP1L1
HBP1
HDAC3
HERPUD1
HIST1H2BN
HLTF
HMGA1
HMGN4
HNRNPUL1
HSPA2
IRF3
ITCH
ITGB5
JUN
KCNMB1
KEL
KHDRBS2
KRR1
KXD1
LILRA3
MAGEA11
MAPK1IP1L
MATK
MDFI
MNS1
MRPS18B
MSC
MTCP1
MTMR9
MVK
MYL6
MYO1F
MYOZ2
NBPF3
NDRG1
NDUFB1
NDUFV1
NINL
NLE1
NONO
NPPB
NSUN4
NTNG2
PCBP1
PDHX
PEF1
PGLS
PLSCR1
POLR2G
POLR3A
POU4F1
POU5F1
PRKCA
PRMT1
PRR13
PRRC2A
PRTFDC1
PRUNE2
PTK2B
RAB37
RAD23A
RALYL
RASL11B
RBPMS
RFX3
RHOXF2
RMND5B
RNF183
RPL31
RPS15A
SALL2
SCMH1
SEC24A
SEC24D
SERP2
SF1
SF3B4
SLC1A1
SLC22A24
SMAD1
SMAD4
SNRPC
SSBP2
SSBP3
SUPT4H1
SUV39H2
TAF1
TFG
TMSB4Y
TONSL
TPGS2
TRAF1
TRAF2
TRAF3
TRIM37
TRIM5
TRPV5
TSPAN3
TULP2
USP7
VPS72
WBP4
WDR37
WWP1
WWP2
YWHAG
YY1AP1
ZBTB1
ZDHHC3
ZNF165
ZNF184
ZNF383
Entrez ID
86
2130
HPRD ID
05389
00592
Ensembl ID
ENSG00000136518
ENSG00000182944
Uniprot IDs
O96019
Q01844
PDB IDs
2CPE
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Chromatin Modification
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of RNA Metabolic Process
Chromatin Organization
Nucleobase-containing Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Aortic Smooth Muscle Cell Differentiation
Regulation Of Metabolic Process
Chromosome Organization
Positive Regulation Of Viral Transcription
Chromatin Remodeling
Negative Regulation Of Cell Cycle
Cellular Response To DNA Damage Stimulus
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Positive Regulation Of Gene Expression
Regulation Of Viral Transcription
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Viral Process
DNA Metabolic Process
DNA Repair
Histone H2A Acetylation
Histone Acetylation
Vascular Smooth Muscle Cell Differentiation
Internal Peptidyl-lysine Acetylation
Positive Regulation Of Transcription, DNA-templated
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Histone Modification
Protein Acetylation
Organelle Organization
Regulation Of Viral Process
Regulation Of Cell Cycle
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Cellular Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Response To Stress
Viral Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
RNA Processing
Negative Regulation Of Gene Expression
Cellular Response To Stress
Regulation Of Establishment Of Protein Localization
Negative Regulation Of Transcription, DNA-templated
MRNA Metabolic Process
MRNA Processing
Apoptotic Process
Regulation Of Intracellular Transport
Response To Virus
Programmed Cell Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Cellular Localization
Regulation Of Cellular Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Protein Transport
Immune System Process
Regulation Of Protein Localization
Cell Death
Defense Response
Death
Regulation Of Cell Death
Tagcloud
?
arranged
blue
cauda
cd99
cords
equina
focal
fusion
glomus
hybridization
immunophenotypic
indolent
infrequent
involving
ki
labeling
longstanding
mitoses
nerve
nests
neu
reverse
roots
rosette
round
smooth
spinal
transcriptase
wt1
Tagcloud (Difference)
?
arranged
blue
cauda
cd99
cords
equina
focal
fusion
glomus
hybridization
immunophenotypic
indolent
infrequent
involving
ki
labeling
longstanding
mitoses
nerve
nests
neu
reverse
roots
rosette
round
smooth
spinal
transcriptase
wt1
Tagcloud (Intersection)
?