EWSR1 and TRPV5

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EWSR1	TRPV5
Gene Name		EWS RNA-binding protein 1	transient receptor potential cation channel, subfamily V, member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Poly(A) RNA Binding	Calcium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Calcium Ion Transport Ion Transmembrane Transport Protein Tetramerization Transmembrane Transport Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport
Pathways			Ion channel transport TRP channels Stimuli-sensing channels
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Protein-Protein Interactions		159 interactors: ACTL6A AGT ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BTK C10orf12 C11orf16 C19orf57 CALM1 CCDC91 CD177 CDK12 CEACAM5 CETP CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DHX9 DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EP300 EPAS1 EPT1 ERCC5 FAM131C FASN FLI1 FUS FXR2 GNPDA1 GPBP1L1 HBP1 HDAC3 HERPUD1 HIST1H2BN HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383	4 interactors: ANXA2 CALB1 EWSR1 S100A10
Entrez ID		2130	56302
HPRD ID		00592	05981
Ensembl ID		ENSG00000182944	ENSG00000127412
Uniprot IDs		Q01844	Q9NQA5
PDB IDs		2CPE
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Viral Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter RNA Processing Negative Regulation Of Gene Expression Cellular Response To Stress Regulation Of Establishment Of Protein Localization Negative Regulation Of Transcription, DNA-templated MRNA Metabolic Process MRNA Processing Apoptotic Process Regulation Of Intracellular Transport Response To Virus Programmed Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Transport Immune System Process Regulation Of Protein Localization Cell Death Defense Response Death Regulation Of Cell Death	Membrane Raft Assembly Protein Heterotetramerization Membrane Raft Organization Membrane Assembly Membrane Biogenesis Establishment Of Protein Localization To Plasma Membrane Membrane Budding Protein Tetramerization Positive Regulation Of Binding Metanephric Connecting Tubule Development Protein Heterooligomerization Protein Localization To Plasma Membrane Vesicle Organization Plasma Membrane Organization Establishment Of Protein Localization To Membrane Metanephric Part Of Ureteric Bud Development Regulation Of Binding Metanephric Distal Convoluted Tubule Development Metanephric Distal Tubule Development Protein Localization To Membrane Osteoclast Development Metanephric Collecting Duct Development Positive Regulation Of Organelle Organization Endomembrane System Organization Distal Tubule Development Protein Oligomerization Collecting Duct Development Short-term Memory Metanephric Nephron Tubule Development Fibrinolysis Positive Regulation Of Vesicle Fusion Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Retina Layer Formation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Protein Targeting To Plasma Membrane Metanephric Epithelium Development Metanephros Morphogenesis Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Vesicle Fusion Negative Regulation Of Blood Coagulation Membrane Organization Positive Regulation Of Stress Fiber Assembly Long-term Memory Osteoclast Differentiation Negative Regulation Of Coagulation Regulation Of Focal Adhesion Assembly Positive Regulation Of Actin Filament Bundle Assembly Collagen Fibril Organization Regulation Of Organelle Organization
Tagcloud ?		arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1	ca2 casr clin collecting excretion extends furosemide handling hypoparathyroidism imcd invest loupy lowers mathematical medullary microperfusion mtal nephron pumps raised reabsorption reproduces romk sensing sigmoidal stone transepithelial tubules vanilloid
Tagcloud (Difference) ?		arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1	ca2 casr clin collecting excretion extends furosemide handling hypoparathyroidism imcd invest loupy lowers mathematical medullary microperfusion mtal nephron pumps raised reabsorption reproduces romk sensing sigmoidal stone transepithelial tubules vanilloid
Tagcloud (Intersection) ?