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EWSR1 and HSPA2
Number of citations of the paper that reports this interaction (PubMedID
16713569
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EWSR1
HSPA2
Description
EWS RNA binding protein 1
heat shock protein family A (Hsp70) member 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Plasma Membrane
Cajal Body
Membrane
Synaptonemal Complex
Male Germ Cell Nucleus
Nucleus
Cytoplasm
Spindle
Cytosol
Cytoskeleton
Plasma Membrane
Cell Surface
Membrane
CatSper Complex
Extracellular Exosome
Blood Microparticle
Meiotic Spindle
Molecular Function
Nucleic Acid Binding
Transcription Coregulator Activity
RNA Binding
Protein Binding
Calmodulin Binding
Zinc Ion Binding
Identical Protein Binding
Metal Ion Binding
Nucleotide Binding
Protein Binding
ATP Binding
ATP Hydrolysis Activity
Enzyme Binding
Heat Shock Protein Binding
Protein Folding Chaperone
Tau Protein Binding
Unfolded Protein Binding
Protein-folding Chaperone Binding
Glycolipid Binding
ATP-dependent Protein Folding Chaperone
Biological Process
Regulation Of DNA-templated Transcription
Protein Folding
Response To Unfolded Protein
Male Meiotic Nuclear Division
Male Meiosis I
Spermatogenesis
Spermatid Development
Response To Heat
Response To Cold
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cell Differentiation
Protein Refolding
Synaptonemal Complex Disassembly
Negative Regulation Of Inclusion Body Assembly
Pathways
Meiotic synapsis
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
PKR-mediated signaling
Drugs
Quercetin
Diseases
Extraskeletal myxoid chondrosarcoma
Myxoid liposarcoma
Ewing's sarcoma
Clear cell sarcoma of soft tissue
GWAS
Breast cancer (
23535729
)
Pancreatic cancer (
25086665
)
Platelet count (
27863252
)
Platelet distribution width (
32888494
)
Appendicular lean mass (
33097823
)
Interacting Genes
164 interacting genes:
ACTL6A
AGT
ANXA11
ARID1A
ATN1
ATPAF2
ATXN3
BAD
BARD1
BLZF1
BNIP3L
BRME1
BTK
C11orf16
CALM1
CCDC7
CCDC91
CD177
CDK12
CEACAM5
CEBPA
CETP
CFAP298
CFDP1
CHERP
CNST
CPSF6
CPSF7
CREBBP
CUEDC2
CXADR
DFFA
DMRTB1
DNAJB3
DYNLL2
E2F8
ECD
ELAVL3
ELAVL4
ELK1
EPAS1
ERCC5
FAM131C
FASN
FLI1
FXR2
GNPDA1
GPBP1L1
H2BC15
HBP1
HDAC3
HERPUD1
HLTF
HMGA1
HMGN4
HNRNPUL1
HSPA2
IRF3
ITCH
ITGB5
JUN
KCNMB1
KEL
KHDRBS2
KRR1
KXD1
LILRA3
MAGEA11
MAPK1IP1L
MATK
MDFI
MNS1
MRPS18B
MSC
MTCP1
MTMR9
MVK
MYL6
MYO1F
MYOZ2
NBPF3
NDRG1
NDUFB1
NDUFV1
NINL
NLE1
NONO
NPPB
NSUN4
NTNG2
OGT
PCBP1
PDHX
PEF1
PGLS
PLSCR1
POLR2G
POLR3A
POU4F1
POU5F1
PRKCA
PRMT1
PRR13
PRRC2A
PRTFDC1
PRUNE2
PTK2B
PTP4A2
RAB37
RAD23A
RALYL
RASL11B
RBPMS
RFX3
RHOXF2
RMND5B
RNF183
RPL31
RPS15A
SALL2
SCMH1
SEC24A
SEC24D
SELENOI
SERP2
SF1
SF3B4
SLC1A1
SLC22A24
SMAD1
SMAD4
SMARCC1
SMARCC2
SNRPC
SSBP2
SSBP3
SUPT4H1
SUV39H2
TAF1
TFG
TMSB4Y
TONSL
TPGS2
TRAF1
TRAF2
TRAF3
TRIM37
TRIM5
TRPV5
TSPAN3
TULP2
USP7
VPS72
WBP4
WDR37
WWP1
WWP2
YWHAG
YY1AP1
ZBTB1
ZDHHC3
ZNF165
ZNF184
ZNF383
14 interacting genes:
APP
BAG4
CDK1
CRBN
EWSR1
FTCD
HSPBP1
MAP3K3
MEOX2
PARP1
RNF144A
SAE1
TRIM38
UBE3A
Entrez ID
2130
3306
HPRD ID
00592
07174
Ensembl ID
ENSG00000182944
ENSG00000126803
Uniprot IDs
A0A0D9SFL3
Q01844
P54652
PDB IDs
2CPE
3I33
4FSV
5FPD
5FPE
5FPM
5FPN
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Nucleus
Regulation Of RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
RNA Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
DNA-templated Transcription
Transcription Regulator Complex
Chromatin Remodeling
MRNA Metabolic Process
Brahma Complex
NpBAF Complex
RNA Metabolic Process
Regulation Of Gene Expression
Nucleic Acid Binding
Chromatin
Single-stranded DNA Binding
Protein-containing Complex
Negative Regulation Of DNA-templated Transcription
Cardiac Conduction System Development
Chromatin Binding
Negative Regulation Of RNA Biosynthetic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Protein Binding
MRNA Transcription
Negative Regulation Of Macromolecule Metabolic Process
Cellular Response To Stress
Nucleosome Disassembly
TORC1 Signaling
Negative Regulation Of Macromolecule Biosynthetic Process
Post-translational Protein Modification
Protein Modification Process
Regulation Of Protein Localization
Regulation Of Circadian Rhythm
Protein Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Cytoplasm
Positive Regulation Of Post-translational Protein Modification
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Adenyl-nucleotide Exchange Factor Activity
Transferase Activity
Protein Localization To Site Of Double-strand Break
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Protein Localization To Nucleus
Positive Regulation Of Protein Localization
Response To Copper Ion
NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity
NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity
Response To Nerve Growth Factor
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Cellular Response To Amyloid-beta
NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity
NAD+-protein-histidine ADP-ribosyltransferase Activity
NAD+-protein-tyrosine ADP-ribosyltransferase Activity
Cellular Response To Nerve Growth Factor Stimulus
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Regulation Of Establishment Of Protein Localization
Amylin Binding
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Toll Signaling Pathway
Pronuclear Fusion
Limb Development
Sperm Entry
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Golgi Lumen Acidification
Negative Regulation Of MRNA Modification
Regulation Of Protein Targeting To Mitochondrion
Protein Sumoylation
Glutamate Formimidoyltransferase Activity
Formimidoyltetrahydrofolate Cyclodeaminase Activity
Modification-dependent Protein Catabolic Process
Regulation Of Post-translational Protein Modification
Regulation Of Primary Metabolic Process
Response To Amyloid-beta
Positive Regulation Of Macromolecule Metabolic Process
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