EWSR1 and NTNG2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EWSR1	NTNG2
Description		EWS RNA binding protein 1	netrin G2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cajal Body Membrane	Extracellular Region Plasma Membrane Membrane Axon Presynaptic Active Zone Membrane Side Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription	Nervous System Development Axonogenesis Regulation Of Neuron Projection Development Cell Differentiation Modulation Of Chemical Synaptic Transmission Postsynaptic Specialization Assembly Synaptic Membrane Adhesion Regulation Of Neuron Projection Arborization Regulation Of Presynapse Assembly Regulation Of Neuron Migration
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases		Extraskeletal myxoid chondrosarcoma Myxoid liposarcoma Ewing's sarcoma Clear cell sarcoma of soft tissue
GWAS		Breast cancer ( 23535729) Pancreatic cancer ( 25086665) Platelet count ( 27863252) Platelet distribution width ( 32888494)	Bell's palsy ( 33602968) Current cigarettes per day in chronic obstructive pulmonary disease ( 29631575) Gout (normal type) ( 32238385) HDL cholesterol levels ( 32109663) Systemic lupus erythematosus ( 18204098)
Interacting Genes		164 interacting genes: ACTL6A AGT ANXA11 ARID1A ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BRME1 BTK C11orf16 CALM1 CCDC7 CCDC91 CD177 CDK12 CEACAM5 CEBPA CETP CFAP298 CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EPAS1 ERCC5 FAM131C FASN FLI1 FXR2 GNPDA1 GPBP1L1 H2BC15 HBP1 HDAC3 HERPUD1 HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 OGT PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B PTP4A2 RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SELENOI SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SMARCC1 SMARCC2 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383	3 interacting genes: ADRA1A CCR2 EWSR1
Entrez ID		2130	84628
HPRD ID		00592	17650
Ensembl ID		ENSG00000182944	ENSG00000196358
Uniprot IDs		A0A0D9SFL3 Q01844	Q96CW9
PDB IDs		2CPE	3TBD 3ZYG 3ZYI
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Nucleus Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Organization RNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-templated Transcription Transcription Regulator Complex Chromatin Remodeling MRNA Metabolic Process Brahma Complex NpBAF Complex RNA Metabolic Process Regulation Of Gene Expression Nucleic Acid Binding Chromatin Single-stranded DNA Binding Protein-containing Complex Negative Regulation Of DNA-templated Transcription Cardiac Conduction System Development Chromatin Binding Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Protein Binding MRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Stress Nucleosome Disassembly TORC1 Signaling Negative Regulation Of Macromolecule Biosynthetic Process	Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Positive Regulation Of Synaptic Transmission Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Chemokine (C-C Motif) Ligand 12 Binding Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Chemokine (C-C Motif) Ligand 2 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis Pilomotor Reflex Alpha1-adrenergic Receptor Activity Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Regulation Of Thymocyte Migration Regulation Of Immune Complex Clearance By Monocytes And Macrophages CCR2 Chemokine Receptor Binding Positive Regulation Of T Cell Extravasation Neuron-glial Cell Signaling Positive Regulation Of Monocyte Extravasation Monocyte Extravasation Regulation Of The Force Of Heart Contraction By Chemical Signal Neutrophil Clearance G Protein-coupled Receptor Activity Positive Regulation Of Cardiac Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Action Potential Adrenergic Receptor Activity Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Glial Cell Migration Negative Regulation Of Heart Rate Inflammatory Response To Wounding Regulation Of Glutamate Receptor Signaling Pathway Positive Regulation Of Striated Muscle Contraction Adult Heart Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Modulation Of Chemical Synaptic Transmission Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of T Cell Chemotaxis Regulation Of T Cell Chemotaxis Negative Regulation Of Type 2 Immune Response
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