EWSR1 and RAB37

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EWSR1	RAB37
Gene Name		EWS RNA-binding protein 1	RAB37, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane	Endosome Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Secretory Granule Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Poly(A) RNA Binding	GTPase Activity GTP Binding GDP Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Rab Protein Signal Transduction Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Protein-Protein Interactions		159 interactors: ACTL6A AGT ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BTK C10orf12 C11orf16 C19orf57 CALM1 CCDC91 CD177 CDK12 CEACAM5 CETP CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DHX9 DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EP300 EPAS1 EPT1 ERCC5 FAM131C FASN FLI1 FUS FXR2 GNPDA1 GPBP1L1 HBP1 HDAC3 HERPUD1 HIST1H2BN HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383	5 interactors: EWSR1 MAL2 RAB5A RABGGTB RIMS1
Entrez ID		2130	326624
HPRD ID		00592	06702
Ensembl ID		ENSG00000182944	ENSG00000172794
Uniprot IDs		Q01844	B7Z3L0 Q96AX2
PDB IDs		2CPE
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Viral Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter RNA Processing Negative Regulation Of Gene Expression Cellular Response To Stress Regulation Of Establishment Of Protein Localization Negative Regulation Of Transcription, DNA-templated MRNA Metabolic Process MRNA Processing Apoptotic Process Regulation Of Intracellular Transport Response To Virus Programmed Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Transport Immune System Process Regulation Of Protein Localization Cell Death Defense Response Death Regulation Of Cell Death	Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Regulation Of Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Synaptic Plasticity Visual Perception Sensory Perception Of Light Stimulus Establishment Of Vesicle Localization Vesicle Localization Regulation Of Endosome Size Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Synaptic Transmission Protein Geranylgeranylation Establishment Of Organelle Localization Calcium Ion-dependent Exocytosis Of Neurotransmitter Organelle Localization Regulation Of Inhibitory Postsynaptic Membrane Potential Protein Prenylation Early Endosome To Late Endosome Transport Synaptic Transmission Glutamate Secretion Regulation Of Secretion Positive Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Synaptic Vesicle Exocytosis Membrane Hyperpolarization Synaptic Vesicle Recycling Sensory Perception Regulation Of Synaptic Vesicle Transport Positive Regulation Of Membrane Potential Regulation Of Smooth Muscle Cell Migration Receptor Internalization Calcium Ion-dependent Exocytosis Regulation Of Filopodium Assembly Cell-cell Signaling Intracellular Protein Transport Regulated Secretory Pathway Synaptic Vesicle Exocytosis Positive Regulation Of Smooth Muscle Cell Proliferation Rab Protein Signal Transduction Acid Secretion Positive Regulation Of Exocytosis Regulation Of Cellular Localization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neurological System Process Receptor Metabolic Process Dicarboxylic Acid Transport Canonical Wnt Signaling Pathway
Tagcloud ?		arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1	colocalized constitutively controlling elucidated gtpase healing immunocytochemical interacting interacts isoforms knockdown lc macrophages munc13 positively rab27b rab30 rab33a rab3b rab40c raw264 secretion sirna skin tnf upregulated vesicles wound
Tagcloud (Difference) ?		arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1	colocalized constitutively controlling elucidated gtpase healing immunocytochemical interacting interacts isoforms knockdown lc macrophages munc13 positively rab27b rab30 rab33a rab3b rab40c raw264 secretion sirna skin tnf upregulated vesicles wound
Tagcloud (Intersection) ?