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PPFIA3 and GIT1
Number of citations of the paper that reports this interaction (PMID
12923177
)
33
Data Source:
HPRD
(in vitro, two hybrid)
PPFIA3
GIT1
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
G protein-coupled receptor kinase interacting ArfGAP 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cell Surface
Presynaptic Active Zone
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Aggresome
Molecular Function
Protein Binding
Protein Binding
ARF GTPase Activator Activity
Zinc Ion Binding
Biological Process
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Regulation Of Short-term Neuronal Synaptic Plasticity
Axon Guidance
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of ARF GTPase Activity
Regulation Of Cytokinesis
Positive Regulation Of GTPase Activity
Ephrin Receptor Signaling Pathway
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Ephrin signaling
Axon guidance
EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
CAST
ERC2
GIT1
PPFIA1
PPFIA2
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
PTPRU
50 interactors:
ADRBK1
ADRBK2
ARHGEF6
ARHGEF7
BARD1
C8orf33
CCDC113
CENPU
CHD3
DDX24
EIF6
GIT2
GRB2
GRK5
GRK6
HAP1
HMOX2
HTT
KIAA1377
KIF1A
LAMTOR5
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SDCCAG3
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
Entrez ID
8541
28964
HPRD ID
04393
06577
Ensembl ID
ENSG00000177380
ENSG00000108262
Uniprot IDs
O75145
Q59FC3
Q9Y2X7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Cell Adhesion
Enzyme Linked Receptor Protein Signaling Pathway
Dephosphorylation
Signaling
Cell Communication
Glutamate Secretion
Signal Transduction
Acid Secretion
Dicarboxylic Acid Transport
Cell Surface Receptor Signaling Pathway
Cellular Response To Stimulus
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Cell-matrix Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Receptor Binding
Cell-substrate Adhesion
Presynaptic Membrane Assembly
Negative Regulation Of Cell Motility
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Cellular Component Movement
Response To Stimulus
Presynaptic Membrane Organization
Negative Regulation Of Locomotion
Negative Regulation Of Actin Filament Bundle Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cellular Protein Modification Process
Corpus Callosum Development
Carboxylic Acid Transport
Organic Acid Transport
Protein Localization To Cell Surface
Negative Regulation Of Protein Localization To Plasma Membrane
Membrane Assembly
RRNA Transcription
Regulation Of Neuron Projection Development
Nervous System Development
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Membrane Biogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cellular Response To Growth Factor Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Response To Growth Factor
Regulation Of Signal Transduction
Regulation Of Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Organonitrogen Compound
Cell Cycle
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Termination Of G-protein Coupled Receptor Signaling Pathway
Regulation Of Intracellular Signal Transduction
Termination Of Signal Transduction
Glutamate Secretion
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Signal Complex Assembly
Regulation Of Neurotransmitter Levels
Cellular Response To Organic Substance
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Dicarboxylic Acid Transport
Fibroblast Growth Factor Receptor Signaling Pathway
Neurotransmitter Transport
Fc Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of Protein Kinase Activity
Cell Projection Organization
Regulation Of Catalytic Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Neurotransmitter Secretion
Regulation Of Kinase Activity
Response To Peptide Hormone
Immune Response-regulating Signaling Pathway
Positive Regulation Of Metabolic Process
Cell-substrate Adhesion
Regulation Of Apoptotic Process
Response To Organonitrogen Compound
Regulation Of Phosphorus Metabolic Process
Response To Peptide
Positive Regulation Of Signal Transduction
Signaling
Acid Secretion
Negative Regulation Of Signal Transduction
Regulation Of Phosphorylation
Tagcloud
?
ancient
autophosphorylation
coordinates
deregulated
dimerization
exchange
gef
git2
gtpase
guanine
hippo
hpo
interacting
mammals
melanogaster
metazoan
oligomeric
originally
pak
pix
polarity
proteomics
rho
rtgef
salvador
scaffold
sterile
undefined
Tagcloud (Difference)
?
ancient
autophosphorylation
coordinates
deregulated
dimerization
exchange
gef
git2
gtpase
guanine
hippo
hpo
interacting
mammals
melanogaster
metazoan
oligomeric
originally
pak
pix
polarity
proteomics
rho
rtgef
salvador
scaffold
sterile
undefined
Tagcloud (Intersection)
?