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GIT1 and RGS2
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
GIT1
RGS2
Description
GIT ArfGAP 1
regulator of G protein signaling 2
Image
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Cytoplasm
Mitochondrion
Endosome
Centrosome
Cytosol
Cytoskeleton
Focal Adhesion
Postsynaptic Density
Membrane
Lamellipodium
Dendrite
Growth Cone
Cell Projection
Neuron Projection
Calyx Of Held
Synapse
Excitatory Synapse
Inhibitory Synapse
Anchoring Junction
Mitotic Spindle Pole
Presynapse
Postsynapse
Glutamatergic Synapse
GABA-ergic Synapse
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Membrane
Molecular Function
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
Protein Phosphatase Binding
Small GTPase Binding
Identical Protein Binding
Gamma-tubulin Binding
Protein-containing Complex Binding
Metal Ion Binding
Scaffold Protein Binding
Structural Constituent Of Postsynaptic Specialization
Protein Tyrosine Kinase Binding
G-protein Alpha-subunit Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
Calmodulin Binding
Adenylate Cyclase Inhibitor Activity
Beta-tubulin Binding
Biological Process
Immunological Synapse Formation
Intramembranous Ossification
Brain Development
Locomotory Behavior
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of ARF Protein Signal Transduction
Negative Regulation Of ARF Protein Signal Transduction
Regulation Of Cytokinesis
Negative Regulation Of Interleukin-1 Beta Production
Synaptic Vesicle Recycling
Cell Redox Homeostasis
Negative Regulation Of Glycolytic Process
Ephrin Receptor Signaling Pathway
Neuron Development
Dendritic Spine Development
Motor Learning
Cellular Response To Lipopolysaccharide
Cellular Response To Epidermal Growth Factor Stimulus
Positive Regulation Of Microtubule Nucleation
Maintenance Of Postsynaptic Specialization Structure
Presynaptic Modulation Of Chemical Synaptic Transmission
Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Negative Regulation Of Inflammatory Response To Wounding
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Receptor Catabolic Process
Response To Amphetamine
Regulation Of Translation
G Protein-coupled Receptor Signaling Pathway
Spermatogenesis
Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Negative Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Neuron Projection Development
Negative Regulation Of Translation
Response To Ethanol
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of JNK Cascade
Brown Fat Cell Differentiation
Relaxation Of Cardiac Muscle
Relaxation Of Vascular Associated Smooth Muscle
Maternal Process Involved In Female Pregnancy
Positive Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway
Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Glycine Import Across Plasma Membrane
Pathways
Ephrin signaling
Ephrin signaling
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
RHOU GTPase cycle
RAC3 GTPase cycle
RHOV GTPase cycle
Activation of RAC1 downstream of NMDARs
G alpha (q) signalling events
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery calcification (
23870195
)
Response to quetiapine in schizophrenia (
29503163
)
Interacting Genes
54 interacting genes:
ARHGEF6
ARHGEF7
BARD1
C8orf33
CENPU
CEP126
CFAP263
CHD3
DDX24
DSCR9
EIF6
ENTR1
GIT2
GRB2
GRK2
GRK3
GRK5
GRK6
HAP1
HMOX2
HSPA13
HTT
KIF1A
KLHL4
LAMTOR5
LPXN
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
61 interacting genes:
ADCY5
ADRA1A
ADRB2
ARFGAP1
BBS10
CALM1
CEP126
CHD3
CIAO1
CLTA
COMT
COPB1
COPB2
CRMP1
CTSB
DDR1
DUSP21
DYNLL1
EGFR
EIF3L
FZD5
GDE1
GIT1
GNA15
GNAI3
GNAQ
GNAS
HAUS5
HSPA8
IER3IP1
KLK8
LIG1
LRFN1
MARCHF6
METTL18
MON1A
MTUS2
NINL
NIPSNAP1
PPP1R9B
PRKCA
PRKCB
PRKCG
PRKCSH
PRKG1
PRKN
RAB2A
RABAC1
RAP1B
REEP5
RIN3
SCN5A
TSPAN15
TUBB2B
UBC
VPS29
WDR74
XRCC6
ZBTB48
ZNF579
ZYX
Entrez ID
28964
5997
HPRD ID
06577
02917
Ensembl ID
ENSG00000108262
ENSG00000116741
Uniprot IDs
Q59FC3
Q9Y2X7
P41220
PDB IDs
2AF0
2V4Z
4EKC
4EKD
Enriched GO Terms of Interacting Partners
?
Beta-adrenergic Receptor Kinase Activity
G Protein-coupled Receptor Kinase Activity
Cytoplasm
Presynaptic Active Zone
Focal Adhesion
Cell Projection
Epidermal Growth Factor Receptor Signaling Pathway
Signal Complex Assembly
Cytoskeleton
Cytosol
ERBB Signaling Pathway
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Synapse
Centrosome
Enzyme-linked Receptor Protein Signaling Pathway
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Regulation Of G Protein-coupled Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Organelle Localization
Transforming Growth Factor Beta Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Kinase Activity
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Protein Kinase Activity
Vesicle Cytoskeletal Trafficking
Positive Regulation Of Calcium Ion Transmembrane Transport
Vesicle Localization
Protein Autophosphorylation
Centriolar Satellite
ATP Binding
Cell Junction Organization
Desensitization Of G Protein-coupled Receptor Signaling Pathway
Neurotrophin TRKA Receptor Binding
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cell-substrate Adhesion
Protein-containing Complex
Cellular Response To Fluid Shear Stress
Synapse Organization
Positive Regulation Of Cilium Assembly
Negative Adaptation Of Signaling Pathway
Positive Regulation Of Lamellipodium Morphogenesis
Establishment Of Organelle Localization
Positive Regulation Of Organelle Organization
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Protein Phosphatase Binding
Tachykinin Receptor Signaling Pathway
Regulation Of Cell Communication
Protein Serine/threonine Kinase Activity
Regulation Of Signaling
Regulation Of Cell Projection Organization
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Guanyl Nucleotide Binding
Calyx Of Held
G-protein Beta/gamma-subunit Complex Binding
Cognition
Nucleotide Binding
Regulation Of Secretion By Cell
Scaffold Protein Binding
Protein-containing Complex Binding
Learning Or Memory
Heterotrimeric G-protein Complex
G Protein-coupled Receptor Binding
Regulation Of Transport
Response To Ketone
Regulation Of Secretion
Enzyme Binding
Histone H3T6 Kinase Activity
Regulation Of Neurotransmitter Secretion
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Response To Corticosterone
Diacylglycerol-dependent Serine/threonine Kinase Activity
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Insulin Secretion
Regulation Of Muscle System Process
Regulation Of Muscle Contraction
Response To Alcohol
Regulation Of Protein Secretion
System Process
Response To Catecholamine
Cytoplasm
Nervous System Process
Adrenergic Receptor Signaling Pathway
Modulation Of Chemical Synaptic Transmission
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Regulation Of Exocytosis
Response To Hormone
Cellular Localization
Protein Kinase C Signaling
Membrane
Regulation Of Peptide Hormone Secretion
Establishment Of Localization In Cell
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Regulation Of Cellular Component Organization
G Protein-coupled Receptor Signaling Pathway
Centrosome
Regulation Of Establishment Of Protein Localization
Response To Psychosocial Stress
Adenylate Cyclase Activator Activity
Intracellular Protein Localization
G Protein Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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