GIT1 and WDR33

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GIT1	WDR33
Gene Name		G protein-coupled receptor kinase interacting ArfGAP 1	WD repeat domain 33
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Membrane Aggresome	Collagen Trimer Nucleus Nucleoplasm Nucleolus MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	Poly(A) RNA Binding
	Biological Process	Axon Guidance Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway	Postreplication Repair MRNA Polyadenylation MRNA Cleavage Spermatogenesis
Pathways		Ephrin signaling Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: ADRBK1 ADRBK2 ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CENPU CHD3 DDX24 EIF6 GIT2 GRB2 GRK5 GRK6 HAP1 HMOX2 HTT KIAA1377 KIF1A LAMTOR5 LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SDCCAG3 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG	14 interactors: CDK4 EEF1G GIT1 KAT7 PFN2 PRMT1 RBM48 SH3GL3 TGFBR1 TP53 UTP14A WWOX ZBTB16 ZHX1
Entrez ID		28964	55339
HPRD ID		06577	11680
Ensembl ID		ENSG00000108262	ENSG00000136709
Uniprot IDs		Q59FC3 Q9Y2X7	Q9C0J8
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Regulation Of Signal Transduction Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Cell Cycle Vascular Endothelial Growth Factor Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Termination Of Signal Transduction Glutamate Secretion Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Signal Complex Assembly Regulation Of Neurotransmitter Levels Cellular Response To Organic Substance Immune Response-regulating Cell Surface Receptor Signaling Pathway Dicarboxylic Acid Transport Fibroblast Growth Factor Receptor Signaling Pathway Neurotransmitter Transport Fc Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Protein Kinase Activity Cell Projection Organization Regulation Of Catalytic Activity Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotransmitter Secretion Regulation Of Kinase Activity Response To Peptide Hormone Immune Response-regulating Signaling Pathway Positive Regulation Of Metabolic Process Cell-substrate Adhesion Regulation Of Apoptotic Process Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Response To Peptide Positive Regulation Of Signal Transduction Signaling Acid Secretion Negative Regulation Of Signal Transduction Regulation Of Phosphorylation	Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Anterior/posterior Pattern Specification Chromatin Organization System Development Negative Regulation Of Cell Differentiation Developmental Process Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Chondrocyte Differentiation Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Death Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Myeloid Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cartilage Development Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Lens Development In Camera-type Eye Multicellular Organismal Development Regulation Of Cell Cycle Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Apoptotic Process Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process Programmed Cell Death Negative Regulation Of Cell Cycle Negative Regulation Of Helicase Activity Signal Transduction By P53 Class Mediator Chromosome Organization Regulation Of Cell Projection Assembly Cell Death Death Pattern Specification Process
Tagcloud ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?