PPFIA3 and PPFIBP1

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vitro)

		PPFIA3	PPFIBP1
Gene Name		protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	PTPRF interacting protein, binding protein 1 (liprin beta 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cell Surface Presynaptic Active Zone	Plasma Membrane Focal Adhesion
	Molecular Function	Protein Binding
	Biological Process	Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Regulation Of Short-term Neuronal Synaptic Plasticity	Cell Adhesion
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRG PTPRS PTPRU	7 interactors: PPFIA1 PPFIA2 PPFIA3 PTPRM S100A4 YWHAG YWHAQ
Entrez ID		8541	8496
HPRD ID		04393	04390
Ensembl ID		ENSG00000177380	ENSG00000110841
Uniprot IDs		O75145	Q86W92
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Dephosphorylation Signaling Cell Communication Glutamate Secretion Signal Transduction Acid Secretion Dicarboxylic Acid Transport Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Cell-matrix Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Cell Migration Negative Regulation Of Receptor Binding Cell-substrate Adhesion Presynaptic Membrane Assembly Negative Regulation Of Cell Motility Phosphate-containing Compound Metabolic Process Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Cellular Component Movement Response To Stimulus Presynaptic Membrane Organization Negative Regulation Of Locomotion Negative Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Protein Modification Process Corpus Callosum Development Carboxylic Acid Transport Organic Acid Transport Protein Localization To Cell Surface Negative Regulation Of Protein Localization To Plasma Membrane Membrane Assembly RRNA Transcription Regulation Of Neuron Projection Development Nervous System Development Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Membrane Biogenesis	Glutamate Secretion Acid Secretion Dicarboxylic Acid Transport Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Carboxylic Acid Transport Organic Acid Transport Establishment Of Localization In Cell Positive Regulation Of Mitochondrion Organization Cellular Localization Organic Anion Transport Secretion By Cell Regulation Of Mitochondrion Organization Synaptic Transmission Secretion Anion Transport Regulation Of Establishment Of Protein Localization Signaling Regulation Of Synaptic Plasticity Cell-matrix Adhesion Cell Communication Regulation Of Protein Localization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cell-substrate Adhesion Cell-cell Signaling Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Regulation Of Cellular Localization Negative Regulation Of Stress Fiber Assembly Regulation Of Synaptic Transmission Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Cell Adhesion Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Transport Positive Regulation Of Organelle Organization Negative Regulation Of Protein Localization To Plasma Membrane Protein Targeting Retinal Ganglion Cell Axon Guidance Regulation Of Intracellular Transport Regulation Of Signaling Retina Layer Formation
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