GIT1 and LAMTOR5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		GIT1	LAMTOR5
Gene Name		G protein-coupled receptor kinase interacting ArfGAP 1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Membrane Aggresome	Lysosome Cytosol Ragulator Complex
	Molecular Function	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process	Axon Guidance Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway	Regulation Of Cell Size Response To Virus Viral Genome Replication Positive Regulation Of TOR Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of GTPase Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways		Ephrin signaling Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: ADRBK1 ADRBK2 ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CENPU CHD3 DDX24 EIF6 GIT2 GRB2 GRK5 GRK6 HAP1 HMOX2 HTT KIAA1377 KIF1A LAMTOR5 LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SDCCAG3 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG	16 interactors: CEP70 EEF1A1 GAPDH GIT1 GPRASP1 KIAA1377 LAMTOR4 LRIF1 MAF1 MEOX2 NCOA6 RABIF TAF9 UTP14A YTHDC1 ZBTB16
Entrez ID		28964	10542
HPRD ID		06577	09773
Ensembl ID		ENSG00000108262	ENSG00000134248
Uniprot IDs		Q59FC3 Q9Y2X7	O43504
PDB IDs			3MS6 3MSH
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Regulation Of Signal Transduction Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Cell Cycle Vascular Endothelial Growth Factor Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Termination Of Signal Transduction Glutamate Secretion Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Signal Complex Assembly Regulation Of Neurotransmitter Levels Cellular Response To Organic Substance Immune Response-regulating Cell Surface Receptor Signaling Pathway Dicarboxylic Acid Transport Fibroblast Growth Factor Receptor Signaling Pathway Neurotransmitter Transport Fc Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Protein Kinase Activity Cell Projection Organization Regulation Of Catalytic Activity Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotransmitter Secretion Regulation Of Kinase Activity Response To Peptide Hormone Immune Response-regulating Signaling Pathway Positive Regulation Of Metabolic Process Cell-substrate Adhesion Regulation Of Apoptotic Process Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Response To Peptide Positive Regulation Of Signal Transduction Signaling Acid Secretion Negative Regulation Of Signal Transduction Regulation Of Phosphorylation	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Transcription Factor TFIIIB Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Gene Expression Neuron Death Nucleobase-containing Compound Metabolic Process G-protein Coupled Receptor Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Embryonic Pattern Specification Protein Stabilization Negative Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Stability Male Germ-line Stem Cell Asymmetric Division Somite Specification Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Glucocorticoid Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Macromolecule Biosynthetic Process
Tagcloud ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?