Wiki-Pi
About
Search
People
Updates
Search
GIT1 and PTPRZ1
Number of citations of the paper that reports this interaction (PubMedID
11381105
)
40
Data Source:
HPRD
(two hybrid, in vivo)
GIT1
PTPRZ1
Description
GIT ArfGAP 1
protein tyrosine phosphatase receptor type Z1
Image
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Cytoplasm
Mitochondrion
Endosome
Centrosome
Cytosol
Cytoskeleton
Focal Adhesion
Postsynaptic Density
Membrane
Lamellipodium
Dendrite
Growth Cone
Cell Projection
Neuron Projection
Calyx Of Held
Synapse
Excitatory Synapse
Inhibitory Synapse
Anchoring Junction
Mitotic Spindle Pole
Presynapse
Postsynapse
Glutamatergic Synapse
GABA-ergic Synapse
Extracellular Region
Plasma Membrane
Membrane
Extracellular Matrix
Synapse
Perineuronal Net
Molecular Function
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
Protein Phosphatase Binding
Small GTPase Binding
Identical Protein Binding
Gamma-tubulin Binding
Protein-containing Complex Binding
Metal Ion Binding
Scaffold Protein Binding
Structural Constituent Of Postsynaptic Specialization
Protein Tyrosine Kinase Binding
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Integrin Binding
Protein Binding
Hydrolase Activity
Biological Process
Immunological Synapse Formation
Intramembranous Ossification
Brain Development
Locomotory Behavior
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of ARF Protein Signal Transduction
Negative Regulation Of ARF Protein Signal Transduction
Regulation Of Cytokinesis
Negative Regulation Of Interleukin-1 Beta Production
Synaptic Vesicle Recycling
Cell Redox Homeostasis
Negative Regulation Of Glycolytic Process
Ephrin Receptor Signaling Pathway
Neuron Development
Dendritic Spine Development
Motor Learning
Cellular Response To Lipopolysaccharide
Cellular Response To Epidermal Growth Factor Stimulus
Positive Regulation Of Microtubule Nucleation
Maintenance Of Postsynaptic Specialization Structure
Presynaptic Modulation Of Chemical Synaptic Transmission
Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Negative Regulation Of Inflammatory Response To Wounding
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Receptor Catabolic Process
Hematopoietic Progenitor Cell Differentiation
Protein Dephosphorylation
Signal Transduction
Axonogenesis
Central Nervous System Development
Learning Or Memory
Neuron Projection Development
Regulation Of Myelination
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of Neuron Apoptotic Process
Oligodendrocyte Differentiation
Positive Regulation Of Oligodendrocyte Differentiation
Regulation Of Oligodendrocyte Progenitor Proliferation
Pathways
Ephrin signaling
Ephrin signaling
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
RHOU GTPase cycle
RAC3 GTPase cycle
RHOV GTPase cycle
Activation of RAC1 downstream of NMDARs
Other interleukin signaling
MDK and PTN in ALK signaling
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Hand grip strength (
27325353
)
Heel bone mineral density (
30598549
)
Lung adenocarcinoma (
28604730
)
Interacting Genes
54 interacting genes:
ARHGEF6
ARHGEF7
BARD1
C8orf33
CENPU
CEP126
CFAP263
CHD3
DDX24
DSCR9
EIF6
ENTR1
GIT2
GRB2
GRK2
GRK3
GRK5
GRK6
HAP1
HMOX2
HSPA13
HTT
KIF1A
KLHL4
LAMTOR5
LPXN
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
13 interacting genes:
ADD2
ALK
ARHGAP35
CTNNB1
FYN
GIT1
HMGB1
IL34
MDK
MGAT5B
PTN
PTPRF
TNR
Entrez ID
28964
5803
HPRD ID
06577
01481
Ensembl ID
ENSG00000108262
ENSG00000106278
Uniprot IDs
Q59FC3
Q9Y2X7
B4DFE7
P23471
PDB IDs
3JXF
3S97
5AWX
5H08
8FN8
8FN9
Enriched GO Terms of Interacting Partners
?
Beta-adrenergic Receptor Kinase Activity
G Protein-coupled Receptor Kinase Activity
Cytoplasm
Presynaptic Active Zone
Focal Adhesion
Cell Projection
Epidermal Growth Factor Receptor Signaling Pathway
Signal Complex Assembly
Cytoskeleton
Cytosol
ERBB Signaling Pathway
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Synapse
Centrosome
Enzyme-linked Receptor Protein Signaling Pathway
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Regulation Of G Protein-coupled Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Organelle Localization
Transforming Growth Factor Beta Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Kinase Activity
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Protein Kinase Activity
Vesicle Cytoskeletal Trafficking
Positive Regulation Of Calcium Ion Transmembrane Transport
Vesicle Localization
Protein Autophosphorylation
Centriolar Satellite
ATP Binding
Cell Junction Organization
Desensitization Of G Protein-coupled Receptor Signaling Pathway
Neurotrophin TRKA Receptor Binding
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cell-substrate Adhesion
Protein-containing Complex
Cellular Response To Fluid Shear Stress
Synapse Organization
Positive Regulation Of Cilium Assembly
Negative Adaptation Of Signaling Pathway
Positive Regulation Of Lamellipodium Morphogenesis
Establishment Of Organelle Localization
Positive Regulation Of Organelle Organization
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Protein Phosphatase Binding
Tachykinin Receptor Signaling Pathway
Regulation Of Cell Communication
Protein Serine/threonine Kinase Activity
Regulation Of Signaling
Regulation Of Cell Projection Organization
Regulation Of Response To Wounding
Cell Migration
Regulation Of Oligodendrocyte Differentiation
Regulation Of Neuron Projection Development
Cell Motility
Positive Regulation Of Neuron Projection Development
Regulation Of Glial Cell Differentiation
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Developmental Process
Positive Regulation Of Oligodendrocyte Differentiation
Regulation Of Cellular Component Organization
Regulation Of Cell Projection Organization
Leukocyte Migration
Regulation Of Gliogenesis
Schaffer Collateral - CA1 Synapse
Positive Regulation Of Leukocyte Chemotaxis
Regulation Of Axon Regeneration
Regulation Of Neuron Projection Regeneration
Neuron Projection Development
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Cell Development
Learning Or Memory
Positive Regulation Of Multicellular Organismal Process
Positive Regulation Of Glial Cell Differentiation
Cell Development
Nervous System Development
Cognition
Positive Regulation Of Chemotaxis
Positive Regulation Of Leukocyte Migration
Growth Factor Activity
Heparin Binding
Positive Regulation Of Blood Vessel Branching
Learning
Positive Regulation Of Cell Projection Organization
Regulation Of Multicellular Organismal Development
Regulation Of Neurogenesis
Enzyme-linked Receptor Protein Signaling Pathway
Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway
System Development
Regulation Of Blood Vessel Branching
Leukocyte Chemotaxis Involved In Inflammatory Response
Positive Regulation Of Gliogenesis
Positive Regulation Of Epithelial Cell Proliferation
Response To Mechanical Stimulus
Cell Projection Organization
Positive Regulation Of Cellular Component Organization
Regulation Of Cell Communication
Signal Transduction
Regulation Of Signaling
Positive Regulation Of Cell Development
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?