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PPFIA3 and PTPRF
Number of citations of the paper that reports this interaction (PMID
9624153
)
49
Data Source:
HPRD
(in vitro, in vivo)
PPFIA3
PTPRF
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
protein tyrosine phosphatase, receptor type, F
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cell Surface
Presynaptic Active Zone
Integral Component Of Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Heparin Binding
Protein Complex Binding
Biological Process
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Regulation Of Short-term Neuronal Synaptic Plasticity
Cell Adhesion
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Cell Migration
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of Receptor Binding
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Amyotrophic lateral sclerosis (age of onset) (
22959728
)
Protein-Protein Interactions
12 interactors:
CAST
ERC2
GIT1
PPFIA1
PPFIA2
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
PTPRU
23 interactors:
BCAR1
CAV1
CDH1
CTNNB1
FRS2
FYN
GALNT1
INSR
IRS1
IRS2
JUP
LCK
NID1
PPFIA1
PPFIA2
PPFIA3
PRPF40A
PTPRA
PTPRD
RET
SKIL
TRIO
ZNF512B
Entrez ID
8541
5792
HPRD ID
04393
01552
Ensembl ID
ENSG00000177380
ENSG00000142949
Uniprot IDs
O75145
P10586
PDB IDs
1LAR
2DJU
2DN7
2EDX
2EDY
2YD5
2YD8
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Cell Adhesion
Enzyme Linked Receptor Protein Signaling Pathway
Dephosphorylation
Signaling
Cell Communication
Glutamate Secretion
Signal Transduction
Acid Secretion
Dicarboxylic Acid Transport
Cell Surface Receptor Signaling Pathway
Cellular Response To Stimulus
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Cell-matrix Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Receptor Binding
Cell-substrate Adhesion
Presynaptic Membrane Assembly
Negative Regulation Of Cell Motility
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Cellular Component Movement
Response To Stimulus
Presynaptic Membrane Organization
Negative Regulation Of Locomotion
Negative Regulation Of Actin Filament Bundle Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cellular Protein Modification Process
Corpus Callosum Development
Carboxylic Acid Transport
Organic Acid Transport
Protein Localization To Cell Surface
Negative Regulation Of Protein Localization To Plasma Membrane
Membrane Assembly
RRNA Transcription
Regulation Of Neuron Projection Development
Nervous System Development
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Membrane Biogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organonitrogen Compound
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Cellular Response To Growth Factor Stimulus
Response To Organonitrogen Compound
Response To Growth Factor
Cellular Response To Organic Substance
Response To Peptide Hormone
Response To Peptide
Response To Organic Substance
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cellular Response To Hormone Stimulus
Cell Adhesion
Insulin Receptor Signaling Pathway
Response To Hormone
Cellular Response To Indole-3-methanol
Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Apoptotic Process
Cellular Response To Insulin Stimulus
Signaling
Regulation Of Cell Death
System Development
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Cell Communication
Locomotion
Regulation Of Signaling
Positive Regulation Of Signal Transduction
Regulation Of Cellular Component Movement
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Glycogen Biosynthetic Process
Response To Insulin
Multicellular Organismal Development
Regulation Of Cell Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Regulation Of Cellular Component Organization
Anatomical Structure Development
Organ Development
Cell Migration
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Cell Motility
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Cell Adhesion
Signal Transduction
Tagcloud
?
1r
abrogated
blue
bombesin
castration
cleavage
clonogenic
conditioned
contributions
docetaxel
endpoints
engineered
lncap
medium
ne
neuroendocrine
neuropeptides
neurotensin
paracrine
parp
pc3
phenomenon
principle
pthrp
secretions
talk
thoroughly
trypan
twofold
Tagcloud (Difference)
?
1r
abrogated
blue
bombesin
castration
cleavage
clonogenic
conditioned
contributions
docetaxel
endpoints
engineered
lncap
medium
ne
neuroendocrine
neuropeptides
neurotensin
paracrine
parp
pc3
phenomenon
principle
pthrp
secretions
talk
thoroughly
trypan
twofold
Tagcloud (Intersection)
?