PPFIA3 and CBY2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPFIA3	CBY2
Description		PPFI scaffold protein A3	chibby family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytosol Cytoplasmic Vesicle Synapse Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse	Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Neurotransmitter Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Adult body size ( 32376654) Leukoderma in response to rhododendrol ( 32558222)
Interacting Genes		17 interacting genes: CAST CBY2 CNKSR1 DISC1 ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PPP1R13B PTPRD PTPRF PTPRS PTPRU SORBS3 TFIP11	119 interacting genes: ACTN1 AIMP2 AIRIM ARHGEF40 ARMC7 BEX3 C19orf44 CCDC146 CCDC185 CCDC187 CCDC198 CCDC57 CCHCR1 CCNG1 CDC23 CDC37 CDK18 CDK2 CEP44 CEP55 CEP57L1 CEP95 CHCHD3 CHIC2 CIBAR1 CKS1B CNNM3 CYTH4 DGCR6 DTNB DUSP14 DZIP1L EFCAB3 EIF4E2 ELOA ENKD1 FAM161A FANCG FARS2 FBXO17 FRS3 GADD45A GADD45GIP1 GOLGA2 GOLGA6A GOLGA6L2 GRAP2 HAUS1 HSF2BP ING5 ISCU KIAA0408 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MCRS1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NEK6 NINL NME7 NTAQ1 OIP5 PID1 PIN1 PLEKHN1 POLR1C PPFIA3 PPP1R13B PPP1R18 PRPF18 PRPF31 RCOR3 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SNAPC5 SSX3 SYCE1 SYT17 TCEA2 TCEANC TCHP TEX11 TRIM42 TRIML2 TSC2 TSGA10 TSGA10IP TUBGCP4 TXK TXLNA TXLNB USHBP1 ZC2HC1C ZFYVE26 ZMAT2 ZNF250 ZNF417 ZNF564 ZNF572 ZNF581 ZNF655 ZNF688 ZNF764 ZNF785
Entrez ID		8541	220082
HPRD ID		04393	14856
Ensembl ID		ENSG00000177380	ENSG00000174015
Uniprot IDs		O75145	A0A140VJV5 Q8NA61
PDB IDs
Enriched GO Terms of Interacting Partners?		Presynaptic Active Zone Synapse Organization Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Regulation Of Dendritic Spine Development Cell Junction Organization Transmembrane Receptor Protein Tyrosine Phosphatase Activity Cell Adhesion Synaptic Membrane Adhesion Protein Tyrosine Phosphatase Activity Maintenance Of Synapse Structure Presynaptic Membrane Phosphoprotein Phosphatase Activity Regulation Of Postsynapse Organization Glutamatergic Synapse Cell Junction Maintenance Cortical Microtubule Organization Axon Presynaptic Active Zone Organization Cellular Component Maintenance Maintenance Of Postsynaptic Specialization Structure Regulation Of Cellular Component Organization Regulation Of Neuron Projection Development Presynapse Protein Dephosphorylation Regulation Of Postsynaptic Density Assembly Modulation Of Chemical Synaptic Transmission Postsynaptic Density Schaffer Collateral - CA1 Synapse GABA-ergic Synapse Presynapse Organization Postsynaptic Density Organization Regulation Of Postsynaptic Specialization Assembly Regulation Of Excitatory Synapse Assembly Peptidyl-tyrosine Dephosphorylation Regulation Of Synapse Organization Synapse Postsynaptic Specialization Organization Dephosphorylation Regulation Of Axon Regeneration Growth Cone Regulation Of Neuron Projection Regeneration Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Cell-substrate Adhesion Neuromuscular Junction Development Regulation Of Response To Wounding Cell Cortex Focal Adhesion Regulation Of Dendritic Spine Morphogenesis	Protein Binding Centrosome Cytoskeleton Centriole Spindle Pole Microtubule-based Process Microtubule Organizing Center Organization Organelle Organization Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Ciliary Basal Body Male Meiosis Chromosome Segregation Microtubule Cytoskeleton Organization Centrosome Cycle Microtubule Binding
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