GIT1 and KIF1A

Number of citations of the paper that reports this interaction (PMID 12522103)
44

Data Source:
HPRD (in vivo)

		GIT1	KIF1A
Gene Name		G protein-coupled receptor kinase interacting ArfGAP 1	kinesin family member 1A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Membrane Aggresome	Cytoplasm Kinesin Complex Microtubule Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	Motor Activity ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Axon Guidance Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway	Microtubule-based Movement Anterograde Axon Cargo Transport Metabolic Process Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport
Pathways		Ephrin signaling Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: ADRBK1 ADRBK2 ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CENPU CHD3 DDX24 EIF6 GIT2 GRB2 GRK5 GRK6 HAP1 HMOX2 HTT KIAA1377 KIF1A LAMTOR5 LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SDCCAG3 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG	26 interactors: ADAMTSL4 AR BZRAP1 ESR1 FXR2 GIT1 MDFI MED1 MID2 MKRN3 MTUS2 NOTCH2NL PLSCR1 PPARG PSMA3 RBPMS RFX6 RGS20 RNF31 RXRA SP1 SPRY2 TNS2 TRAF1 TRIM27 TRIP6
Entrez ID		28964	547
HPRD ID		06577	03156
Ensembl ID		ENSG00000108262	ENSG00000130294
Uniprot IDs		Q59FC3 Q9Y2X7	G1UI30 Q12756
PDB IDs			4EGX 4EJQ
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Regulation Of Signal Transduction Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Cell Cycle Vascular Endothelial Growth Factor Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Termination Of Signal Transduction Glutamate Secretion Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Signal Complex Assembly Regulation Of Neurotransmitter Levels Cellular Response To Organic Substance Immune Response-regulating Cell Surface Receptor Signaling Pathway Dicarboxylic Acid Transport Fibroblast Growth Factor Receptor Signaling Pathway Neurotransmitter Transport Fc Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Protein Kinase Activity Cell Projection Organization Regulation Of Catalytic Activity Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotransmitter Secretion Regulation Of Kinase Activity Response To Peptide Hormone Immune Response-regulating Signaling Pathway Positive Regulation Of Metabolic Process Cell-substrate Adhesion Regulation Of Apoptotic Process Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Response To Peptide Positive Regulation Of Signal Transduction Signaling Acid Secretion Negative Regulation Of Signal Transduction Regulation Of Phosphorylation	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA-templated Transcription, Initiation Hormone-mediated Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Reproductive Structure Development Reproductive System Development Regulation Of Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Metabolic Process Placenta Development Intracellular Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Branch Elongation Of An Epithelium Positive Regulation Of Signal Transduction Steroid Hormone Mediated Signaling Pathway Signaling Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Communication Regulation Of Establishment Of Protein Localization Regulation Of RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Involved In Reproduction Axis Elongation Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Signal Transduction Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Regulation Of Cellular Process RNA Biosynthetic Process Regulation Of Protein Localization Positive Regulation Of Gene Expression Branch Elongation Involved In Mammary Gland Duct Branching Negative Regulation Of Signaling Single Organism Reproductive Process Regulation Of Viral Process Regulation Of Protein Import Into Nucleus Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Regulation Of Protein Transport
Tagcloud ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1
Tagcloud (Difference) ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1
Tagcloud (Intersection) ?