PPFIA3 and PTPRS

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vitro)

		PPFIA3	PTPRS
Gene Name		protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	protein tyrosine phosphatase, receptor type, S
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cell Surface Presynaptic Active Zone	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Regulation Of Short-term Neuronal Synaptic Plasticity	Cell Adhesion Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Extracellular Matrix Organization Peptidyl-tyrosine Dephosphorylation
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses	ECM proteoglycans
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRG PTPRS PTPRU	23 interactors: CHD3 EEF1G EGFR FEZ1 KAT5 KIAA1377 MOB4 PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 TUBB2A UBR1 UNC119 UTP14A
Entrez ID		8541	5802
HPRD ID		04393	03344
Ensembl ID		ENSG00000177380	ENSG00000105426
Uniprot IDs		O75145	Q13332 Q59FX6 Q8NHS7
PDB IDs			2FH7 2YD2 2YD3 2YD9 4BPC
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Dephosphorylation Signaling Cell Communication Glutamate Secretion Signal Transduction Acid Secretion Dicarboxylic Acid Transport Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Cell-matrix Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Cell Migration Negative Regulation Of Receptor Binding Cell-substrate Adhesion Presynaptic Membrane Assembly Negative Regulation Of Cell Motility Phosphate-containing Compound Metabolic Process Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Cellular Component Movement Response To Stimulus Presynaptic Membrane Organization Negative Regulation Of Locomotion Negative Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Protein Modification Process Corpus Callosum Development Carboxylic Acid Transport Organic Acid Transport Protein Localization To Cell Surface Negative Regulation Of Protein Localization To Plasma Membrane Membrane Assembly RRNA Transcription Regulation Of Neuron Projection Development Nervous System Development Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Membrane Biogenesis	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Glutamate Secretion Protein Dephosphorylation Acid Secretion Dephosphorylation Dicarboxylic Acid Transport Neurotransmitter Secretion Cellular Response To Estradiol Stimulus Regulation Of Neurotransmitter Levels Cellular Response To Estrogen Stimulus Positive Regulation Of Vasodilation Axon Guidance Amino Acid Transport Neuron Differentiation Neurotransmitter Transport Cell Projection Organization Signaling Cell Adhesion Cell Communication Regulation Of Vasodilation Neuron Projection Development Negative Regulation Of Epithelial Cell Migration Response To Estrogen Cell Projection Morphogenesis Cellular Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Cell Part Morphogenesis Secretion By Cell Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Cellular Response To Organic Substance Cell-cell Signaling Axonogenesis Cellular Response To Amino Acid Stimulus Regulation Of Stress Fiber Assembly Neuron Development Cellular Protein Modification Process Axon Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Astrocyte Activation Dense Core Granule Maturation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Regulation Of Dendrite Morphogenesis Chemotaxis Cell Cycle Process
Tagcloud ?			cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4
Tagcloud (Difference) ?			cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4
Tagcloud (Intersection) ?