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PPFIA3 and CAST
Number of citations of the paper that reports this interaction (PMID
12923177
)
33
Data Source:
HPRD
(in vitro, two hybrid)
PPFIA3
CAST
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
calpastatin
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cell Surface
Presynaptic Active Zone
Cytoplasm
Cytosol
Membrane
Molecular Function
Protein Binding
Endopeptidase Inhibitor Activity
Cysteine-type Endopeptidase Inhibitor Activity
Protein Binding
Poly(A) RNA Binding
Biological Process
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Regulation Of Short-term Neuronal Synaptic Plasticity
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Calcium
Diseases
GWAS
Alcohol dependence (
19581569
)
Protein-Protein Interactions
12 interactors:
CAST
ERC2
GIT1
PPFIA1
PPFIA2
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
PTPRU
10 interactors:
CAPN1
CAPNS1
CASP1
CASP3
CASP7
HTRA1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
Entrez ID
8541
831
HPRD ID
04393
00233
Ensembl ID
ENSG00000177380
ENSG00000153113
Uniprot IDs
O75145
P20810
Q59HE3
Q86YM9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Cell Adhesion
Enzyme Linked Receptor Protein Signaling Pathway
Dephosphorylation
Signaling
Cell Communication
Glutamate Secretion
Signal Transduction
Acid Secretion
Dicarboxylic Acid Transport
Cell Surface Receptor Signaling Pathway
Cellular Response To Stimulus
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Cell-matrix Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Receptor Binding
Cell-substrate Adhesion
Presynaptic Membrane Assembly
Negative Regulation Of Cell Motility
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Cellular Component Movement
Response To Stimulus
Presynaptic Membrane Organization
Negative Regulation Of Locomotion
Negative Regulation Of Actin Filament Bundle Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cellular Protein Modification Process
Corpus Callosum Development
Carboxylic Acid Transport
Organic Acid Transport
Protein Localization To Cell Surface
Negative Regulation Of Protein Localization To Plasma Membrane
Membrane Assembly
RRNA Transcription
Regulation Of Neuron Projection Development
Nervous System Development
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Membrane Biogenesis
Glutamate Secretion
Acid Secretion
Dicarboxylic Acid Transport
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Execution Phase Of Apoptosis
Carboxylic Acid Transport
Organic Acid Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Extracellular Matrix Disassembly
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Proteolysis
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Endopeptidase Activity
Organic Anion Transport
Positive Regulation Of Peptidase Activity
Secretion By Cell
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Synaptic Transmission
Regulation Of Cysteine-type Endopeptidase Activity
Secretion
Anion Transport
Protein Processing
Positive Regulation Of Proteolysis
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell-cell Signaling
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Endopeptidase Activity
Regulation Of Peptidase Activity
Mitochondrial Depolarization
Positive Regulation Of Interleukin-1 Alpha Secretion
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Dentinogenesis
Positive Regulation Of Cell Death
Cell-matrix Adhesion
Regulation Of Proteolysis
Regulation Of Cell Proliferation
Positive Regulation Of Interleukin-1 Alpha Production
Pyroptosis
Signaling
Intrinsic Apoptotic Signaling Pathway
Cell Communication
Glial Cell Apoptotic Process
Tagcloud
?
absent
antiserum
b1
cardiomyocyte
discs
doubt
dreifuss
dystrophy
edmd
emerin
emery
explanation
intercalated
intranuclear
lamin
lamina
lap1
lap2
lbr
libraries
localize
mabs
muscular
myocyte
nuclei
phage
recognize
rim
spots
Tagcloud (Difference)
?
absent
antiserum
b1
cardiomyocyte
discs
doubt
dreifuss
dystrophy
edmd
emerin
emery
explanation
intercalated
intranuclear
lamin
lamina
lap1
lap2
lbr
libraries
localize
mabs
muscular
myocyte
nuclei
phage
recognize
rim
spots
Tagcloud (Intersection)
?