RHOXF2 and VAC14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		RHOXF2	VAC14
Description		Rhox homeobox family member 2	VAC14 component of PIKFYVE complex
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Golgi Membrane Endosome Endoplasmic Reticulum Cytosol Endosome Membrane Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex Presynaptic Endosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Neuron Development	Phosphatidylinositol Biosynthetic Process Signal Transduction Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways			Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS			Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Pulse pressure ( 28135244)
Interacting Genes		101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CIMIP2A CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683	107 interacting genes: ABHD11 ACSS1 ACTMAP AMT APP ARID5A ASB13 ATM BCL2L1 BHLHE40 BKGD C4orf33 CASP1 CATSPERT CD209 CDRT4 CNTN2 COL8A1 CRK CRYBA1 CRYBA2 DDAH2 DNAAF19 EEF1AKMT3 EHHADH EIF2S1 EIF6 FAM50B FNDC3B GABPB2 GALT GINS3 GLIS2 GNB1 GTF3C2 HDHD3 HNF1B HNRNPLL INTS11 JMJD7 KHDC1 KRABD5 KRT82 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LINC00518 LPAL2 MBLAC1 MEOX2 METTL15 MGAT5B MPPED2 MTMR9 MVP MYOZ1 NDUFAB1 NGB NOS1 NTAQ1 OIT3 OTOS PBLD PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PPP6C PRADC1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX2 RHBDL1 RHOXF2 RIPPLY1 RNASEH2C RSKR SIGLEC5 SMUG1 SNF8 SPMIP9 SPRYD7 SRPK2 TCEANC TP53BP1 TRIM55 TRIM63 UFSP1 VENTX VHLL WDR83 WRAP53 ZBTB49 ZCWPW1 ZNF34
Entrez ID		84528	55697
HPRD ID		02345	07660
Ensembl ID		ENSG00000131721	ENSG00000103043
Uniprot IDs		Q9BQY4	Q08AM6
PDB IDs			7K1Y
Enriched GO Terms of Interacting Partners?		Intermediate Filament Regulation Of MRNA Metabolic Process Poly(A) RNA Polymerase Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Stabilization Protein Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of RNA Splicing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability Regulation Of MRNA Processing Procollagen Galactosyltransferase Activity Transcription Factor Binding Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Nucleus Small Protein Activating Enzyme Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Anoikis Negative Regulation Of Metabolic Process RNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Anoikis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Stress Granule	Protein Binding Intermediate Filament
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